• 한국지역사회생활과학회지
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• 제23권4호
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• pp.383-397
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• 2012

The incidence of zoonoses in Korea has recently increased. But the study for high risk group such as pig farmers to zoonoses has not been conducted in Korea. Thus we reviewed the articles in order to obtain basic data for zoonoses among pig farmers, especially in rural communities. Pigs are one of the most important domestic livestock in Korea not only from economic standpoint but also from standpoint of food. Pigs also represent a potential reservoir for many novel pathogens, therefore may transmit these to humans via direct contact, vectors such as mosquitos, or contaminated meat. The zoonoses associated with pigs can be classified into bacterial pathogen, viruses and so on. Bacterial zoonoses include brucellosis, leptospirosis, listeriosis, enterohemorrhagic Escherichia coli infection, pasteurellosis, salmonellosis, yersiniosis, tuberculosis, anthrax, necrobacillosis, swine erysipelas, erysipeloid, melioidosis, Streptococcus suis infection, Clostrium difficile infection, and campylobactor infection. Viral zoonoses consist of Japanese encephalitis, swine influenza, Nipah virus, Reston ebolavirus, and hepatitis E virus infection. Other type of zoonoses include actinomycosis, toxoplasmosis and Taenia solium infection. These zoonoses were important in Korean health policy but lately they have been overlooked. For effective health policy, we need to study zoonoses associated with pigs, and clinicians and veterinarians must care deeply about these zoonoses.

• 한국산업보건학회지
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• 제26권4호
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• pp.418-425
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• 2016

Objectives: General livestock farmers are known as a high riskgroup for zoonoses, but studies of general livestock farmers in regard tozoonoses have been rare in Korea. We surveyed awareness of zoonoses amonggeneral livestock farmers to suggest directions for education. Methods: A questionnaire was developed examining the workbehaviors and risk factors of general livestock farmers. We conducted a questionnairesurvey on awareness on zoonoses among 265 general livestock farmers. Results: The awareness rates for zoonosis itself,brucellosis, and q-fever were 13.0%, 65.0%, and 2.3%, respectively. The awarenessrate of zoonoses and brucellosis tended to increase with sex. Conclusions: Livestock is the principal reservoir ofzoonoses. Therefore, effective working guidelines for preventing zoonoses amonggeneral livestock farmers must be developed and an educational program onzoonoses is needed for general livestock farmers. Furthermore, publicityactivities on the prevention of zoonoses are needed for high-risk groups.

• 대한수의학회지
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• 제60권3호
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• pp.173-177
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• 2020

Edible offal is easily contaminated by Escherichia coli (E. coli) and fluoroquinolone (FQ)-resistant E. coli is considered a serious public health problem, thus, this study investigated the genetic characteristics of FQ-resistant E. coli from edible offal. A total of 22 FQ-resistant E. coli isolates were tested. A double mutation in each gyrA and parC led the highest MIC. Four (18.2%) isolates carried plasmid-mediated quinolone resistance genes. The fimH, eaeA, escV, astA, and iucC genes were confirmed. Seventeen isolates (77.3%) were positive for plasmid replicons. The isolates showed high genetic heterogeneity based on pulsed-field gel electrophoresis patterns.

• 한국식품과학회지
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• 제5권2호
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• pp.108-112
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• 1973

저자(著者)는 식품(食品)에 기인(起因)하는 질환(疾患)의 요인(要因)이 될 수 있는 식품위생학상(食品衛生學上) 중요(重要)한 zoonoses 의 국내발생(國內發生) 양상(樣相)을 알아 보고자 시도(施導)하여 국내(國內)의 각종(各種) 기초자료(基礎資料)를 분석(分析) 통계처리(統計處理) 하여 보았든 바 다음의 몇가지 결과(結果)를 얻었다. (1) 국내(國內)에서 발생(發生)한 사람에서의 zoonoses 는 1962년(年)부터 1966년도(年度)까지 5 개년(個年) 간(間)에 anthrax 3 예(例), brucellosis 2 예(例), erysipeloid 140 예(例) 로서 앞으로 계속적인 조사(調査)가 요구(要求) 되었다. (2) 국내(國內)에는 670 개소(個所)의 도축장(屠畜場)이 있으며, 연도별(年度別) 도축검사중(屠畜檢査中) 불허건수(不許件數)는 과거(過去) 10 개년간(個年間)에 우(牛)가 전도축우(全屠畜牛)의 $0.45{\sim}0.98%$, 돈(豚)가 $0.005{\sim}0.05%$로서 돈(豚)보다 우(牛)의 경우가 많았다. (3) Epidemiological pattern 별(別) 국내발생(國內發生) zoonoses 를 가축(家畜)에서 조사(調査)한 바에 의(依)하면; (a) Direct-zoonoses 로서 anthrax, brucellosis 및 erysipelas 가 있었으며, 우(牛)의 anthrax 가 최고발병율(最高發病率)로는 1964년도(年度)의 1.7(per 100,000)이었고, 유우(乳牛)의 brucellosis는 1960 년도(年度)의 1338.4, 돈(豚)의 erysipelas 는 1962 년도(年度)의 1897.2 이었다. (b) Cyclo-zoonoses 중(中) 우리나라 돈(豚)의 cysticercus cellulosae 의 감염율(感染率)은 육지(陸地)의 경우 $1.0{\sim}2.7%$ 제주도(濟州道)의 경우 $3.8{\sim}8.5%$까지 감염율(感染率)이 있음을 문헌(文獻)에 의(依)하여 알 수 있었다.

• Journal of Microbiology and Biotechnology
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• 제25권5호
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• pp.606-611
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• 2015

As Salmonella enterica serovar Pullorum remains a major economic problem for the poultry industries of countries with no efficient control measures, we presented a multidrug resistance strain S06004 (isolated from a clinically sick chicken in China in 2006) for genome sequencing. The genome comparison showed that the strain contained two prophages, the ST104 and prophage-4 (Fels2) of E. coli LF82, which were not detected in the only published genomes of S. Pullorum RKS5078 and CDC1983-67. In addition, the GyrA Ser83 point mutation, drugresistant genes, and many antibiotic pump systems that are present in S06004 may be contributing to the multidrug resistance of this strain.

• 농촌의학ㆍ지역보건
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• 제44권1호
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• pp.39-42
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• 2019

Zoonoses are the diseases that are transmitted to human being from vertebrate animals either from livestock animals or from wildlife. Recently, zoonoses are increasingly common as a result of incremental human-animal contact. Propagative infections in wild animals and livestock are transmitted to human beings who are encountered with them. In general, wild animals can transmit infectious agents to livestock, and then livestock further transmit them to human being is a simple model of on how zoonotic diseases get transmitted to human being. This model emphasizes the importance of early detection of zoonoses by surveillance at its incipient stage. Cooperation between the respective ministries plays an important role in the identification of zoonoses and planning for the formulation of better preventive and control policy and strategy. We will be able to predict the occurrence of zoonotic diseases in human on the basis of disease trends in wildlife and livestock once when we obtain the surveillance data and data generated by respective ministries through sound cooperation and collaboration.

• 한국가금학회지
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• 제37권4호
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• pp.331-336
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• 2010

We evaluated the immunomodulatory effects of proanthocyanidin-rich extract (PAE) from Pinus radiata bark in broiler. Proliferation of peripheral blood mononuclear cells and thymocytes was significantly enhanced in 2.5, 5, 10 mg/kg PAE-treated broiler chickens. Proliferation of splenocytes was significantly enhanced in 1.25, 2.5, 5, 10 mg/kg PAE-treated broiler chickens. These effects were markedly enhanced by the presence of LPS, which acts on B cells responsible for humoral immunity, and Con A, which acts directly on T cells involved in cell mediated immunity. PAE significantly promoted the expression of interleukin-18 and interleukin-$1\beta$. Thus, PAE from P. radiata possesses immunomodulatory effects in broiler chickens.

• Journal of Microbiology and Biotechnology
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• 제24권3호
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• pp.363-370
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• 2014

Campylobacter jejuni is a prevalent foodborne pathogen worldwide. Human infection by C. jejuni primarily arises from contaminated poultry meats. Genes expressed in vivo may play an important role in the pathogenicity of C. jejuni. We applied an immunoscreening method, in vivo-induced antigen technology (IVIAT), to identify in vivo-induced genes during human infection by C. jejuni. An inducible expression library of genomic proteins was constructed from sequenced C. jejuni NCTC 11168 and was then screened using adsorbed, pooled human sera obtained from clinical patients. We successfully identified 24 unique genes expressed in vivo. These genes were implicated in metabolism, molecular biosynthesis, genetic information processing, transport, and other processes. We selected six genes with different functions to compare their expression levels in vivo and in vitro using real-time RT-PCR. The results showed that the selected six genes were significantly upregulated in vivo but not in vitro. In short, these identified in vivo-induced genes may contribute to human infection of C. jejuni, some of which may be meaningful vaccine candidate antigens or diagnosis serologic markers for campylobacteriosis. IVIAT may present a significant and efficient method for understanding the pathogenicity mechanism of Campylobacter and for finding targets for its prevention and control.

• Parasites, Hosts and Diseases
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• 제58권4호
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• pp.457-460
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• 2020

The Pacific tapeworm Adenocephalus pacifcus (syn. Diphyllobothrium pacificum) is a causative agent of diphyllobothriosis occurred in Pacific coast of South America, mainly in Peru. Source of infections are traditional meal from raw or undercooked marine fish such as "cebiche". We confirmed 3 new cases, one including scolex and the other two headless. A strobila 46 cm long without scolex was discharged from an 8-year-old boy before treatment. Specimens were confirmed morphologically by presence of tegumental protuberances on proglottids and small sized eggs. Partial sequence of cytochrome c oxidase subunit 1 gene was congruent with A. pacificus sequences.

• 농촌의학ㆍ지역보건
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• 제39권4호
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• pp.222-229
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• 2014

지금까지 다른 고위험군들에 비해 상대적으로 양돈 종사자에 대한 연구가 드물었고, 돼지가 인수공통감염병의 주요 병원소로 국내에서도 돼지와 관련된 인수공통감염병이 지속적으로 발생하고 있는 상황에서 이번 연구는 양돈 종사자들을 대상으로 인수공통감염병에 대한 인지도를 파악해 보고자 진행하였다. 2012년도에 경상남도 권역, 경상북도 권역, 전라남도 권역, 충청남도 권역 등 4개 권역의 양돈협회 자체교육에 참여한 양돈 종사자 중 278명을 대상으로 자체 개발하여 농업기술원의 전문가 23명을 대상으로 타당성 조사를 마친 설문지를 활용하여 일 대 일 면접방식으로 설문조사를 진행하였다. 인수공통감염병의 인지율은 살모넬라증 89.6%, 결핵 87.8%, 브루셀라증 85.6% 등의 순으로 개별 인수공통감염병에 대해서는 80% 이상 인지하고 있었지만 인수공통감염병 자체에 대한 인지율은 52.9%이었고, 돼지의 질병이 사람에게 감염될 수 있다고 응답한 대상자는 46.9%에 불과하였다. 연구 대상자들의 개별 특성 및 양돈 작업관련 특성 중 인수공통감염병 인지율에 미치는 영향을 파악해 본 결과 대학 졸업이상의 학력을 가진 대상자들이 중학교 졸업 이하의 학력을 가진 대상자들에 비해 인수공통감염병 자체는 3.1배, 살모넬라증은 6.0배 더 잘 인지하고 있었다. 또한 양돈업에 10년 미만 종사한 대상자들에 비해 30년 이상과 20-29년 종사한 대상자들이 각각 6.2배와 7.9배 더 잘 살모넬라증을 인지하고 있었다. 이처럼 국내의 양돈 종사자들은 브루셀라증, 살모넬라증, 결핵 등 각각의 인수공통감염병에 대해서는 잘 인지하고 있었지만 인수공통감염병이라는 용어 자체와 돼지의 질병이 사람에게도 감염될 수 있다는 특성은 절반 정도만이 인지하고 있었다. 이번 연구에서 고학력일수록, 양돈업에 종사기간이 길수록 인수공통감염병 및 살모넬라증을 더 잘 인지한다고 밝혀진 것처럼, 교육 및 관련 정보에의 노출이 인지율을 높일 수 있는 가장 좋은 방법일 것이다. 돼지는 다양한 인수공통감염병의 주요한 병원소인 만큼, 향후 양돈 종사자들을 대상으로 인수공통감염병의 개념 및 감염경로를 포함하는 체계적인 교육과 정보제공이 지속적으로 이루어져야 할 것이다.