Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)
- 2003.09b
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- Pages.219-238
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- 2003
CLINICAL EFFICACY EVALUATION OF O/W EMULSION CONTAINING INDOLE-3-ACETIC ACID WITH THE FUNCTION OF ANTI-WRINKLE
- Yang, Jae-Hun (School of Chemistry ＆ Molecular Engineering, Seoul National University) ;
- Lee, Sun-Young (Nanohybrid Co. Ltd) ;
- Han, Yang-Su (Nanohybrid Co. Ltd) ;
- Jung, Hye-Sun (Cosmax Inc) ;
- Kim, Ju-Ho (Cosmax Inc) ;
- Park, Kwon-Ho (Cosmax Inc) ;
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Choy, Jin-Ho
(School of Chemistry ＆ Molecular Engineering, Seoul National University)
- Published : 2003.09.01
Abstract
Indole-3-acetic acid (IAA) molecule has been successfully encapsulated in biocompatible inorganic matrix in order for the cosmetic application such as superfacial fine line reduction. The encapsulation was realized through chemical reaction involving simultaneous formation of inorganic lattice and 1M giving rise to an 1M-inorganic nanohybrid (IAA-brid) which shows excellent storage stability and sustained releasing property of indole-3-acetic acid. The clinical efficacy of essence cream containing IAA-brid as anti-wrinkle formulation was also carefully evaluated by measuring the roughness of the skin replica before and after treatment. Upon administration of the cream on the eye-area, the fine-line is drastically reduced.