Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)

Society of Cosmetic Scientists of Korea (대한화장품학회)
권호 표지

DEVELOPMENT OF ANALYYICAL METHOD OF DMDM HYDANTOIN, SORBIC ACID, PHENOXY ETHANOL IN COSMETICS

  • K. H. Son (Drug Evaluation Department, Korea Food and Drug Administration) ;
  • Kim, Y. O. (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • J. Y. Jang (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Lee, J. P. (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • S. J. Yang (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Lee, K. S. (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • W. J. Yang (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Kim, C. K. (College of Pharmacy, Chung-Ang Universit) ;
  • Park, S. S. (Drug Evaluation Department, Korea Food and Drug Administration)
  • Published : 2003.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

A high-performance liquid chromatographic method for the simultaneous quantitative analysis of DMDM hydantoin, sorbic acid, phenoxy ethanol in cosmetics was studied by using a X-terra C$\sub$18/ column and 0.75mM KH$_2$PO$_4$ in 0.85% sulfuric acid and methanol mixture(7:3) at 214nm. Calibration curves were found to be linear in the 20-100 $\mu\textrm{g}$/mL range (DMDM hydantoin), 50-250 $\mu\textrm{g}$/mL range (sorbic acid) and 10-50 $\mu\textrm{g}$/mL range (phenoxy ethanol). The result of recovery test were 96.6% ∼ 104.2%. This HPLC method can be applied quality control of cosmetics.

Keywords