Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)

Society of Cosmetic Scientists of Korea (대한화장품학회)
권호 표지

STUDIES ON THE IN VITRO SPF TEST METHOD OF SUNSCREEN PRODUCTS

  • K. H. Son (Drug Evaluation Department, Korea Food and Drug Administration) ;
  • Kim, Y. O. (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Lee, J. P. (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • S. J. Yang (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Kim, W. H. (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Kim, C. K. (College of Pharmacy, Chung-Ang Universit) ;
  • M. Y. Heo (College of Pharmacy, Kangwon National Universit) ;
  • S. J. Jang (Drug Evaluation Department, Korea Food and Drug Administratio) ;
  • Park, S. S. (Drug Evaluation Department, Korea Food and Drug Administration)
  • Published : 2003.09.01
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Abstract

The present study was undertaken to develop the in vitro sun protection factor(SPF) test method having good correlation with in vivo method using human. 8% homomentyl salicylate, P3 reference standard and commercially available sunscreen products were measured by the in vitro method using SPF 290S analyzer, and the SPFs were compared with the SPFs measured by in vivo test method. In vitro SPFs of 8% HMS and P3 reference standard were 4.59 $\pm$ 0.12 and 14.94 $\pm$ 0.83. There are good correspondence, correlation coefficients were 0.9506 and 0.9769 respectively, between the in vitro and in vivo SPFs for the sunscreen creams and lotions. Correlation coefficients of makeup base/liquid foundation, lotion labled with "shake before use" and compact powder were 0.8812, 0.8632 and 0.5984 respectively. The optimum mixture ratio of compact powder and cream base represents 1:0.8. These results suggest that the in vitro SPF test method will be able to be used as an alternative method for in vivo SPF in case of lotion and cream.

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