Proceedings of the SCSK Conference (대한화장품학회:학술대회논문집)

Society of Cosmetic Scientists of Korea (대한화장품학회)
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TYROSINASE INHIBITORY ACTIVITY OF LONICERA JAPONICA

  • Lai, Jeng-Shiow (Department of Cosmetic Science, Providence University) ;
  • Su, Chen-Wen (Institute of Applied Chemistry, Providence University) ;
  • Huang, Keh-Feng (Institute of Applied Chemistry, Providence University)
  • Published : 2003.09.01
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Abstract

A tyrosinase inhibitor, Lonjapoin, was isolated from the ethanolic extracts of Flos Lonicera by activity-guided fractionation. Lonjapoin ($IC_{50}$/; 2.07 $\mu\textrm{g}$/mL) was found to be potentially as effective inhibitor of production of melamin. Flos Lonicera (Jinyinhua) is the dry flower buds of Lonicera japonica. Thunb. It is used as an antibacterial and antiphlogistic agent in the treatment of abscess, laryngeal catarrh, erysipelas, dysentery, cold and fever. In our continuing search for natural source as cosmetic ingredients from Chinese medicinal herbs and found the extracts of Flos Lonicera showed the significant tyrosinase inhibition activity. In this study the active constituent of Lonicera japonica. obtained with the process of tyrosinase activity assay and column chromatography.

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