Inhibitory Action of Phenylpropanoids on Histamine Release from Rat Peritoneal Mast Cells

  • Lee, Jin-Hee (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Lee, Ji-Yun (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Kim, Youn-Joung (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Kim, Tae-Doo (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Yoon, Mi-Yun (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Sim, Sang-Soo (Department of Pathophysiology, College of Pharmacy, Chung Ang University) ;
  • Kim, Chang-Jong (Department of Pathophysiology, College of Pharmacy, Chung Ang University)
  • Published : 2003.04.01

Abstract

Phenylpropanoids originating from vegetable kingdom have some biological activity. In this experiments, effect of phenylpropanoids on the histamine release from mast cells were studied in vitro. Rat peritoneal mast cells were isolated by the discontineous gradients of Percoll and their histamine release by stimulation of compound 48/80 and A23187 at a concentration of 6.0 $\mu\textrm{g}$/$m\ell$ were determined. (omitted)

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