대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.212.2-212.2
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- 2003
Hepatoprotective effects and Mechanism of Flavonoids
- Kim, Young-Gwan (College of Pharmacy, Kyung Hee university) ;
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Kim, Dong-Hyun
(College of Pharmacy, Kyung Hee universit)
;
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Lee, Kyung-Tae
(College of Pharmacy, Kyung Hee university)
- 발행 : 2003.04.01
초록
Primary cultured rat hepatocytes injured by carbon tetrachloride as a model to screen for hepatoprotective effect. Four flavonoid compounds showed anti-hepatotoxic effect by decrease GPT. LDH activity and MDA level. Also screen for hepatoprotective, anti-oxidative and anti-apoptosis effects of baicalin and baicalein on chang cell treated with t-BHP. Mesured radical detoxifying enzyme, GST and antioxidant enzyme SOD, Catalase activity, GSH level and Cellular glutathion peroxidase activity. (omitted)
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