Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Alteration of Cellular Adhesion Molecules during Aging and Their Modulation by Calorie Restriction

  • Zou, Yani (College of Pharmacy, Pusan National University) ;
  • Kim, You-Jung (Department of Cosmetology, Pusan Women′s Colleg) ;
  • Kim, Ji-Young (Department of Cosmetology, Pusan Women′s Colleg) ;
  • Kang, Dae-Yoen (Department of Cosmetology, Pusan Women′s Colleg) ;
  • Kim, Nam-Deuk (Department of Cosmetology, Pusan Women′s Colleg) ;
  • Lee, Kyung-Hee (Department of Cosmetology, Pusan Women′s Colleg) ;
  • Chung, Hae-Young (Department of Cosmetology, Pusan Women′s College)
  • Published : 2003.04.01
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Abstract

Expressions of cellular adhesion molecules (CAMs) are closely related to the formation of early atherosclerosis, an age-dependent vascular disorder. However. previous research provided only limited and conflicted reports on age-related alterations of CAMs' expressions and even much less is known the modulation of CAMs by calorie restriction (CR), In this study, expression of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), E-selectin, P-selectin and platelet/endothelial cell adhesion molecule-1 (PECAM-1) in aorta and kidney were investigated by western blot and immuno-histochemical stain utilizing ad libitum (AL) and CR rat. (omitted)

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