Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.245.1-245.1
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- 2003
Polyoxygenated Flavone Analogs as Inhibitors of PGE2 Production
- Kim, Jeong-Soo (College of Pharmacy, Kangwon National University) ;
- Tran, Thanh-Dao (College of Pharmacy, Seoul National University) ;
- Chi, Yeon-Sook (College of Pharmacy, Seoul National University) ;
- Kim, Hyun-Pyo (College of Pharmacy, Seoul National University) ;
- Kim, Sang-Hee (College of Pharmacy, Seoul National University) ;
- Park, Hae-Il (College of Pharmacy, Seoul National University)
- Published : 2003.04.01
Abstract
As part of our research to discover novel synthetic flavonoids which can be applied to chronic inflammation diseases, many structurally modified flavone analogs have been synthesized to obtain information concerning the relationships between structures and the anti-inflammatory activities. We previously reported that 7-methoxyflavone analogs generally exhibited strong inhibitory activities against cyclooxygenase-2 catalyzed prostaglandin production. (omitted)
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