YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Mutagenicity by Several Fractions of Organic Matter Extracted from Airborne Particulates Collected in atmosphere

대기중 부유분진에 함유된 유기물의 분획별 돌연변이원성

  • Jang, Jae-Yeon (College of Pharmacy, Seoul National University) ;
  • Kim, Bak-Kwang (College of Pharmacy, Seoul National University) ;
  • Chung, Yong (The Institute for Environmental Research, Yonsei University)
  • 장재연 (서울대학교 약학대학) ;
  • 김박광 (서울대학교 약학대학) ;
  • 정용 (연세대학교 환경공해연구소)
  • Published : 1989.02.28
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Abstract

The extractable organic matter was extraced from airborne particulates collected in Seoul during 1986. It was fractionated to several fracrtions and mutagenicities of them were tested in Salmonella thyphimurium TA98 by Ames method. The neutral fraction showed the highest indirect acting mutagenicity while the highest direct acting mutagenicity was observed in the acidic fraction. Indirect acting mutagenicity of airborne particulate was attributed to its neutral fraction about 88% in average, to acidic about 10% in average and to basic fraction about 2% in average. Direct acting mutagenicity of airborne particulate was attributed to its neutral fraction about 70%, to acidic fraction about 29% and to basic fraction about 1%. Among five subfractions of neutral fraction, the proportion of mutagenicity of polynuclear aromatic hydrocarbon subfraction was 13.2% in indirect acting mutagenicity and 5.0% in direct acting mutagenicity.

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