Archives of Pharmacal Research

  • 제12권2호
  • /
  • Pages.135-137
  • /
  • 1989
  • /
  • 0253-6269(pISSN)
  • /
  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Synthesis of 2-Substituted 4H-Thieno[2,3-b][1]benzothiopyran-4-ones as Potential Chemotherapeutic Agents

  • El-Subbagh, H.I. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • Yousif, M.Y. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • El-Eman, A.A. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura) ;
  • El-Kerdawy, M.M. (Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura)
  • 발행 : 1989.06.01
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초록

A convenient route is reported for the synthesis of certain series of 4H-thieno[2,3-b][1]benzothiopyran-4-ones, carrying various substituents at position 2 such as arylazomethines (7,8), thiazolidin-4-ones (9-13), ${\alpha},\;{\beta}-unsaturated$ ketones (16,17), 2-pyridones (19-23), tetrahydrothiophen-4-ones (24,28), and nitroalkenes (29,30), as potential schistosomicidal or antihistaminic agents.

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