Effect of Substrate Micellization on the Hydrolysis Rate of Phospholipid by Phospholipase $A_2$

Phospholipase $A_2$에 의한 인지질의 가수분해반응에서 기질의 미셀화가 반응속도에 미치는 영향

  • 김형주 (건국대학교 공과대학 미생물학과) ;
  • 신우진 (건국대학교 공과대학 미생물학과) ;
  • 최태부 (건국대학교 공과대학 미생물학과)
  • Published : 1993.04.01

Abstract

The effect of substrate micellization on the hydrolysis rate in the production of lysopho-sphatidylcholine (LPC) from phosphatidylcholine (PC) using hog pancreas phospholipase A2(PLA2) was studied. The optimal temperature and pH for the reactions in aqueous phase was found 42C and 7.2, respectively. For a given PC concentration, initial reaction rate was progressively increased with the addition of sodium deoxycholate (DOC), which could transform the bilayer of phospholipids into micellar structure.

Keywords

References

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