Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Taxonomy, Purification and Physicochemical Properties of Novel Antifungal Antibiotics AF-011A

신규 항진균 물질 AF-011A의 생산균주 동정, 정제 및 물리 화학적 특성

  • 김성호 (제일제당(주)종합연구소) ;
  • 현봉철 (제일제당(주)종합연구소) ;
  • 서정우 (제일제당(주)종합연구소) ;
  • 김창완 (제일제당(주)종합연구소) ;
  • 연창석 (제일제당(주)종합연구소) ;
  • 이덕근 (제일제당(주)종합연구소) ;
  • 김광표 (제일제당(주)종합연구소) ;
  • 정재경 (제일제당(주)종합연구소) ;
  • 임융호 (제일제당(주)종합연구소)
  • Published : 1993.12.01
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Abstract

AF-011A is a novel lipopeptide with potent antifungal activity isolated from Pseudomonas cepacia AF6008 deposited as KFCC 10759. The compound was isolated from the fermentation broth by extraction with 50% isopropyl alcohol. Purification was effected by chromatography on Diaion HP-20, Alumina and C18 followed by HPTLC on silica gel. These techniques affored two closelt related compounds. AF-011A1 ans AF-011A2. The molecular weights of AF-011A1/A2 were determined by fast atom bombardment mass spectrometry(A1 m/z 1,215 : A2 m/z 1,199).

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References

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