Microbiology and Biotechnology Letters (한국미생물·생명공학회지)

The Korean Society for Microbiology and Biotechnology (한국미생물·생명공학회)
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Antitumoral Compound, MCS-202, an Effector on Proliferation and Morphology of Human Breast Tumor Cell Line, MCF-7

인체유암세포주 MCF-7의 형태변화와 증식에 영향을 주는 항암활성물질, MCS-202

  • Published : 1993.12.01
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Abstract

In the course of screening for microbial metabolites employing human cancer cell line, we identified a mycelial extract of Streptomyces sp. 1365, which are effective on growth inhibition and morphological change of MCF-7, human breasr cancer cell line. By repeased column chromatography and recrystallization process, yellow needle crystals were obtained as an active compound and identified as resistomycin by spectral analysis.

Keywords

References

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