Journal of Nutrition and Health

  • 제31권2호
  • /
  • Pages.143-152
  • /
  • 1998
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  • 2288-3886(pISSN)
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  • 2288-3959(eISSN)
한국영양학회 (The Korean Nutrition Society)
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분자량이 다른 키토산이 흰쥐의 지방대사에 미치는 영향

Effects of CHitosan of Different Molecular Weights n Lipid Metaboism in Rats

  • 이종미 (이화여자대학교 식품영양학과)
  • 발행 : 1998.02.01
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초록

This study was conducted to investigate the effects of chitosan, chitosan oligomer and beef tallow of different levels on lipid metabolism in rats, Seventy male rats of the Sprague-Dawley strain were blocked into 10 groups according to body weight , and were raised for 4 weeks. Dietary fat levels were 20% en and 40% en, and chitosan and chitosan oligomer were given at levels of 05, 3%, and 5%(wt/wt) of diet. The results are summarized as follows, chitosan oligomer supplement decreased serum total lipid, as chitosan 양, and exhibited a tendency to decrease serum total cholesterol. Chitosan oligomer supplement tended to increase the HDL cholesterol ; total cholesterol ration as chitosan did. Liver total lipid and triglyceride concentration were lower in high fat groups than in low fat groups. Liver total lipid concentrations was decreased slightly by chitosan and sigfnificantly by chitosna ligomer. Epididymal fat pad total lipid. total cholesterol and triglyceride concentration were slightly decreased by chitosan and chitosan oligomer supplement, especially in high fat groups. fat absorptivity was decreased by low fat level, chitisan and chitosan oligamer supplement. Fecal excretion of total lipid and triglyceride were increased by high fat level, chitosan and chi샌무 oligomer supplement. However, fecal excretion of total cholesterol was increased by high fat level and chitosan supplement. This indicated that chitosan and chitosan oligomer were effective in interfering with lipid and triglyceride absorption, In conclusion, chitosan oligomer at levels of 3% and 5% has more effective lipid, cholesterol and triglyceride lowering activity than chitosan.

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참고문헌

  1. Elsevier A pplied Science An overview of the regulation status and of the safety of chitin and chitosan as food and pharmaceutical ingredients Weiner,M.L.
  2. Food Technol v.38 no.1 Use of chitinous polymers in food Knorr,D.
  3. Science v.22 New facts of research Austin,P.R.;Brine,C.J.;Castle,J.E.;Zikakis,J.P.
  4. Food Technol v.44 no.1 Recovery and utilization of chitin and chitosan in food processing waste management Knorr,D.
  5. J Food Sci v.47 Bioconversion of shellfish chitin waste : weste pretreatment, enzyme production, process design and economic analysis Casio,I.G.;Fisher,R.A.;Carroad,P.A.
  6. Processings from the 4th International Conference in chitin and chitosan held in Trondheim Production and application of chitin and chitosan Hirano,S.
  7. Processings from the 4th International Conference in chitin and chitosan held in Trondheim Chitosan, commerical uses and potential application Sanford,P.S.
  8. J Food Sci v.53 Effects of chitosan on yield and compositional data of carrot and apple juice Knorr,D.;Imeri,A.G.
  9. J Food Sci v.54 Effect of chitosan treatments on the clarity and color of apple juice Soto-peralta,N.V.;Muller,H.A.;Knorr,D.
  10. J Food Sci v.48 Effect of chitin as coagulating aid on protein yield, composition and functionality of tomato seed protein concentrates Latlief,S.J.;Knorr,D.
  11. J Foodd Sci v.48 Dye binding properties of chitin and chitosan Knorr,D.
  12. J Food Sci v.54 Recovert of amino acids from seafood proceeding waste treatment with a dual chitosan-based ligand-exchange system No,H.K.;Meyers,S.D.
  13. Food Sci Technol v.24 no.1 A basic study on chitin from krill and kruma prown for industrial use Yang,Y.;Hyun,J.H.;Hwang,Y.H.
  14. Korean J Food Sci Technol v.24 no.6 Physical properties of chitosan film made from crab shell Cho,J.S.;Han,J.J.;Lee,C.H.
  15. Food Industry v.106 Production and development of chitin,chitosan and its derivatives Kim,S.K.
  16. Am J Clin Nutr v.38 Compatative effects of chitosan and cholestyamine on lymphatic absorption of lipids in the rat Vahony,G.V.;Satchihanardam,S.;Cassidy,M.M.;Lightfoot,F.B.;Furda,I.
  17. Am J Clin Nutr v.33 A novel use of chitosan as a hypocholesterelemic agent in rats Sugano,M.;Fujikawa,T.;Hiratsuji,Y.;Nakashima,K.;Hasegawa,Y.
  18. Nutr Rept Int v.19 no.3 Hypochliesterelemic effect of chitosan Kobayashi,T.;Otsuka,S.;Yugari,Y.
  19. Br J Nutr v.72 Effect of chitosan on nutrient digestibility and plasma lipid concentrations in broiler chickens Razdan,A.;Pettersson,D.
  20. Nutr Rep Int v.20 The hypolipidemic activity of chitosan and other polysaccharides in rats Nagyvary,J.J.;Falk,J.D.;Hill,M.L.;Schmidt,M.L.;Wilkins,A.K.;Bradbury,E.L.
  21. Nutr Rep Int v.18 no.5 Hypocholesterolemic effects of chitosan in cholesterol-fed rats Sugano,M.;Fujikawa,T.;Hiratsuji,Y.;Hasegawa,Y.
  22. Proceedings of the society for experimental biology and medicine v.189 A comparison of the lipid-lowing and intestinal morphological effects of cholestyramine, chitosan, and oat gum in rats Jennings,C.D.;Boleyn,K.Bridges,S.R.;Wood,P.J.;Anderson,J.W.
  23. Lipids v.26 Effect of chitosan feeding on intestinala bile acid metabolism in rats Fukada,Y.;Kimura,K.;Ayaki,Y.
  24. J Food Sci v.47 Funcational properties of chitin and chitosan Knorr,D.
  25. Elsyier Applied Science. Chitin and chitosan. Allan,G.G.;Petron,M.
  26. Report of investigation into national nutrition The ministry of health and welfare
  27. Korea rural economic institute Food balance sheet
  28. Research paper of development work on health medical art Production of chito-oligomer and development of functional food Park,H.K.
  29. Adv in Lipid Res v.6 Practical methods for plasma lipoprotein analysis Hatch,F.T.;Lees,R.S.
  30. J Clin Invest v.34 Chemical composition of ultracentrigually separated lipoproteins in human serum Havel,R.d.
  31. Am J Clin Nutr v.53 A colorimetric method for determination of total serum lipids based on the sulfuric-phospho-vanillin reaction Frings,C.S.;Dunn,R.T.
  32. Standard method of clinical chemistry. Total and free cholesterol Zak,B.
  33. Can J Biochem Physiol v.37 A rapid method of total lipid extraction and purification Bligh,E.G.;Dyer,W.J.
  34. J Biol Chem v.226 A simple method for the isolation and purification of total lipids from animal tissues Folch,J.;Lees,M.;Stanley,G.S.H.
  35. Korean J Nutr v.27 no.10 Effect of dietary chitin and chitosan on cadmium toxicity and lipid metabolism in rats Kim,M.K.;Seol,E.Y.
  36. Endocrinology Some effects of chitosan on liver function in the rat LeHoux,J.;Grondin,F.
  37. In new developments in dietary fiber. Interaction of dietary fiber with lipids-mechanistic theories and their limitations Furda,I.
  38. Gut v.22 Effect of gel forming gums on the intestinal unstirred layer and sugar transport in vitro Johnson,I.T.;Gee,J.M.
  39. Lipids v.23 Hypocholesterolemic action of chitosan with different viscosity in rats Sugano,M.;Watanabe,S.;Kishi,A.;Izume,M.;Ohtakara,A.
  40. Korean J Food Sci Technol v.26 no.4 vitro study on the functionality in digestive tract of chitin and chitosan from crab shell Chang,H.J.;Chun,D.W.;Lee,S.R.
  41. Lipids v.18 The binding of micellar lipids to chitosan Nauss,J.L.;Thompson,J.L.;Naajvary,J.