The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Effects of Hyulbuchukotang (HCE) on the Thrombosis Related Factors

혈부축어탕(血府逐瘀湯)이 혈전생성관여인자(血栓生成關與因子)에 미치는 영향(影響)

  • Park, Jong-Hyung (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Han, Yang-Hi (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Jun, Chan-Yong (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Kim, Dong-U (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Park, Se-Gi (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Lee, Chung-Jung-Hye (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Go, Seung-Hi (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Go, Jae-Chul (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Choi, You-Kyung (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University) ;
  • Kim, Young-Sun (Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University)
  • Published : 2000.12.30
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Abstract

Purpose : To investigate the inhibitory effect of HCE on platelet aggragation and erythrocyte deformiability, we performed following experiments. Methods : Concentrated Hyulbuchukotang (HCE) was fed to rats for 10days. We compare normal group with $500{\beta}{\Sigma}/{\beta}{\Sigma}$-high dose group and $100{\beta}{\Sigma}/{\beta}{\Pi}$-low dose group. Results : HCE enhanced the blood filtration rate, erythrocyte deformiability, reduced the platelet aggreablilty and inhibited granule release from collagen stimulated platelet, the prostaglandin synthesis in platelat. Conclusion : HCE should inhibit thrombos formation due to platelet hyperaggraeability and reduction of erythrocyte defonmiability.

Keywords

References

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