Journal of Acupuncture Research

  • 제17권2호
  • /
  • Pages.247-259
  • /
  • 2000
  • /
  • 2586-288X(pISSN)
  • /
  • 2586-2898(eISSN)
대한침구의학회 (Korean Acupuncture & Moxibustion Medicine Society)
권호 표지

핵의학(SPECT)을 이용한 뇌혈류변화에 대한 침구효과 검증방법의 새로운 모델에 관한 연구

New Model of Verifiation for Demonstration of Neuronal Basis of Acupuncture by Comparison of Two Different Methods of Acupuncture which Increase Regional Cerebral Blood Flow ( rCBF ) on SPECT

  • 안수기 (원광대 한의과대학 침구학교실) ;
  • 강화정 (동신대 한의과대학 내과학교실) ;
  • 송호천 (전남대 의과대학 핵의학교실) ;
  • 범희승 (전남대 의과대학 핵의학교실)
  • Ahn, Soog-Gi (Dept. of Acupuncture, Wonkwang University Hospital) ;
  • Kang, Hwa-Jeong (Dept. of Internal Medicine, Dongsin University Hospital) ;
  • Song, Ho-Chun (Dept. of Nuclear Medicine, Chonnam National University Hospital) ;
  • Bom, Hee-Seung (Dept. of Nuclear Medicine, Chonnam National University Hospital)
  • 발행 : 2000.06.20
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Objective : The mechanism of acupuncture to increase cerebral blood flow is still uncertain. The purpose of this study was to evaluate the neural basis of acupuncture by comparing the cerebral regions activated by the stimulation of two different methods of acupunctures at the same acupoint which was suggested by oriental medicine to increase rCBF. Materials and Methods : Thirty-nine healthy volunteers(26 males, 13 females, age $31{\pm}11$ years) were studies by rest/acupuncture Tc-99m ECD brain SPECT using a subtraction method. SPECTs using two methods(needle retention and heated needle with 90% alcohol) at two acupoints (right LI. 4 and ST. 36) were peformed at an interval of three days. For the needle retention method, acupuncture needle was inserted to a depth of about 2 cm into each acupoint 8 minutes after the lst acquisition and continued to retain, and the second injection of Tc-99m ECD was done 15 minutes after the insertion of needle. For the heated acupuncture method, heated needle was inserted in a twinkle within several msec 20 second after the second injection of Tc-99m ECD. The differences of between rest and acupuncture activation state were statistically analyzed using a statistical parametric mapping software. Result : Acupunctures of both methods reveal similar patterns of increase in rCBF. Acupuncture at ST.36 increase rGBF in left anterior temporal, right inferior frontal lobes, and left cerebellum. Acupuncture at LI. 4 increase rCBF in the left frontal cortex, right temporal pole, both inferior frontal cortices and right cerebellum. Conclusion : The effects of two different acupunctures to the same acupoints on rCBF were similar. Therefore, this result suggests Chat the mechanism of acupuncture in the increase of cerebral blood flow have a neural basis.

키워드

과제정보

연구 과제 주관 기관 : 한의학연구원

참고문헌

  1. 東醫學辭典 科學百科辭典綜合出版社
  2. 東醫臨床指鍼 v.67 金康植
  3. 임상중풍학 김영석
  4. 最新鍼灸學 金賢濟(外)
  5. 醫學綱目 權英
  6. 火鍼 劉保延
  7. 鍼灸學 楊甲三
  8. 黃帝內經素問譯解 楊推傑
  9. 鍼灸治療學 임종국
  10. 鍼灸學(상) 전국한의과대학 침구 경혈학교실(편)
  11. 鍼灸學(하) 전국한의과대학 침구 경혈학교실(편)
  12. 鍼灸學(下) 崔容泰(外)
  13. 鍼具鍼法 賀普仁
  14. 경락의 연구Ⅰ 한의학연구소 임상연구부
  15. 경락의 연구∏ 한의학연구소 임상연구부
  16. 경락의 신연구 한국한의연구소 임상연구부
  17. 핵의학입문 핵의학교육연구회
  18. 大韓鍼灸學會誌 v.15 no.2 手陽明大腸經과 관련된 經穴과 顔面神經의 標識領域의 관한 硏究 朴禹順(外)
  19. 대한침구학회지 v.13 중풍의 침구치료에 대한 소고 박진웅(外)
  20. 대한침구학회지 v.15 no.2 화침요법의 연구동향과 DITI를 활용한 임상적 고찰 안수기;박상준
  21. 대한침구학회지 v.15 no.2 鍼法에 따른 合谷穴 刺戟이 疼痛抑制에 미치는 影響 윤여중(外)
  22. 대한침구학회지 v.16 no.1 合谷穴位鍼刺와 電氣刺戟이 疼痛抑制에 미치는 影響 황병천(外)
  23. 대한침구학회지 v.16 no.1 合谷(LI4)刺鍼이 腹部의 溫度變化에 미치는 影響 黃宰浩(外)
  24. Annual Report on the cause of death statistics National Statistical Office Republic of Korea
  25. J Tradit Chin Med v.9 Acupuncture treatment of 60 cases of mumbness due to cerebral arteriosclerosis. Cheng BG
  26. J Tradit Chin Med v.8 Ye MF Hemorrheological study on the effect of acupuncture in treating cerebral infarction Chen JF
  27. Proc Natl Acad Sci USA. v.95 New findings of the corresponding brain cortices using functional MRI. Cho ZH;Chung SC;Jones JP;Park JB;Park HJ;Lee HJ;Wong Ek;Min BI
  28. Neurosci Lett v.141 Measuring the neuromodulatory effects of drugs on man with positron emission tomography. Friston KJ;Grasby PM;Bench CJ;Frith CD;Cowen PJ;Liddle PF; Frackowiak RS;Dolan R.
  29. Neurosci Lett v.13 Brain functional activity during gait in normal subjects: a SPECT study. FukuyamaH, H;Ouchi Y;Matsuaki S;Nagahama Y;Yamauchi H;Ogawa M;Kimura J;Shibasaki H.
  30. Brain v.117 A graded task approach to the functional mapping of brain areas implicated in auditory-verbal memory. Grasby PM;Frith CD;Friston KJ;Simpson J;Fletcher PC;Frackowick RS;Dolan RJ
  31. Neuroepidemiology v.12 A randomized controlled trial on the treatment for acute partial ischemic stroke with acuyuncture. Hu HH;Chung C;Liu TJ;Chen RC;Chen CH;Chou P;Huang WS;Lin JC;Tsuei JJ
  32. Chung Hsi I CHieh Ho Tsa Chih v.3 Effect of acupuncture on cerebral blood flow of cats with experimental cerebral ischemia. Jiang DS
  33. Chen Tzu Yen Chiu v.21 Effects of electrical acupuncture on the cerebral blood flow and the pial microcirculatory blood flow in dogs. Ji G;Zhao L;Shi R;Liu Y;Wang S;Wu F
  34. Stroke v.28 Perspectives of stroke in persons living in seoul,south korea. A survey of 1000 subjects JS Kim;SS Yoon
  35. Korean J Nucl Med v.32 Functional brain mapping using $H_2^15$position emission tomography (Ⅰ): Statistical Parametric Mapping Method. Lee Ds;Lee JS;Kim KM;Chung J.K.;Lee MC.
  36. Korean J Nucl Med v.32 Functional brain mapping using $H_2^15$position emission tomography (∏):Mapping of human working memory. Lee JS;Lee DS;Lee SK:Nam HW;Kim SK
  37. CHung Hsi I Chieh Ho Tsa Chih v.9 Clinical research on 50 cases of stable stage apoplexy treated by acupuncture using brain activating and consciousness regaining principles. Li L;SHi XM
  38. J Cereb Blood Flow Metab. v.16 Position emission tomographic imaging of serotonin activation effects on prefrontal cortex in healthy volunteers. Mann JJ;Malone KM;Diehl DJ;Perel J;Nicols TE;Mintun MA
  39. J Nucl Med v.38 SPECT image analysis using statistical parametric mapping:comparison of technetium-99m-HMPAO and technetium-99m-ECD. Patterson JC;Early TS;Martin A;Walker MZ;Russel JM;Villanueva Meyer H.
  40. Korean J Nuci Med v.33 Change of cerebral blood flow distribution of and vascular reserve according to age in koreans measured by Tc-99m HMPAO brain SPECT. Song HC;Borm HS;Sohn HK;Jeong HJ;Min JJ;Kim JY(et al)
  41. Chung Kuo Chung Hsi I Chieh Ho Tsa CHih v.16 Effect of acupuncture on regional cerebral blood flow and cerebral functional activity evaluated with single-photon emission computed tomography. Wang F;Jia SW
  42. Am J Chin Med v.23 Non-invasive measurement of brain activity using functional MRI:toward the study of brain response to acupuncture stimulation. Yoshida T;Tanaka C;Umeda M;Higuchi T;Fukunaga M