Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Effect of Polyphenol Compounds from Persimmon Leaves (Diospyros kaki folium) on Antiallergy

감잎(Diospyros kaki folium) Polyphenol 화합물군의 알레르기 저해효과

  • Park, Mu-Hee (Dept. of Food Science and Technology, Yeugnam University) ;
  • Choi, Cheong (Dept. of Food Science and Technology, Yeugnam University) ;
  • Son, Gyu-Mok (Dept. of Food and Nutrition, Changwon Junior College) ;
  • An, Bong-Jeon (Faculty of Life Resources and Engineering, Kyungsan University) ;
  • Bae, Man-Jong (Faculty of Life Resources and Engineering, Kyungsan University)
  • 박무희 (영남대학교 식품가공학과) ;
  • 최청 (영남대학교 식품가공학과) ;
  • 손규목 (창원전문대학 식품영양과) ;
  • 안봉전 (경산대학교 생명자원공학부) ;
  • 배만종 (경산대학교 생명자원공학부)
  • Published : 2000.02.01
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Abstract

This study was conducted to investigate antiallergy of the polyphenol fractions isolated from persimmon leaves (Diospyros kaki folum). The result of the passive cutaneous anaphylaxis (PCA) reaction of expriment on anti-allergy, the allergy remarkably decreased in polyphenol fraction I, II and III groups in comparison with the control group. After antigen challenge, histamine content of blood of the polyphenol groups was lowered to near the normal group.

한국산 감잎으로부터 분리한 폴리페놀 화합물군으로부터 알레르기 저해효과에 관한 연구 결과를 얻고자 수동피부 아니필락니스 반응에 대한 효과 및 비만세포에서 유리되는 히스타민의 유리억제능을 관찰하였다. 수동피부 아나필락시스에서는 대조군에 비하여 모든 군에서 유의하게 격감되었으며, 3차에 걸친 항원투여 기간에 있어서도 이러한 경향은 계속되었으며, 항원 투여 후 혈중의 히스타민을 측정한 결과 거의 정상군에 가깝게 혈중 히스타민 함량을 낮추는 역할을 하였다. 이러한 결과는 알레르기 치료제들이 갖는 부작용을 최소화시킬 수 있는 새로운 치료제로서의 가능성을 보여주는 것으로 사료된다.

Keywords

References

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