Sjogren′s Syndrome Combined with MALT Lymphoma

MALT 림프종을 수반한 쉐그렌 증후군

  • Han Won-Jeong (Department of Oral & Maxillofacial Radiology, School of Dentistry, Dankook University) ;
  • Cha Sang-Yun (Department of Oral & Maxillofacial Radiology, School of Dentistry, Dankook University) ;
  • Kim Eun-Kyung (Department of Oral & Maxillofacial Radiology, School of Dentistry, Dankook University)
  • 한원정 (단국대학교 치과대학 구강악안면방사선학교실) ;
  • 차상윤 (단국대학교 치과대학 구강악안면방사선학교실) ;
  • 김은경 (단국대학교 치과대학 구강악안면방사선학교실)
  • Published : 2000.06.01

Abstract

Sjogren's syndrome is a chronic inflammatory disease that predominantly affects salivary, lacrimal and other exocrine glands. We report a case of Sjogren's syndrome combined with MALT (mucose associated lymphoid tissue) lymphoma which occured in the parotid gland. A 57-year-old female with the complaint of painful swelling and lymph node enlargement was referred to our department. Sialograms of both parotid glands showed globular collections of contrast material uniformly distributed throughout the parotid gland. Salivary scintigraphy showed decreased uptake of the parotid gland. CT scan showed larger, slightly more dense parotid gland than normal and honeycomb glandular appearance. Also, It showed discrete, slightly more enhanced round mass in the left parotid gland. Histopathological finding showed replacement of salivary gland parenchyma with dense small lymphocytic infiltration having the feature of epimyoepithelial islands. Kappa light chain restriction of interglandular plasma cell could be seen.

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