Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
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Cytotoxic Constituents of Chelidonium majus var. asiaticum

애기똥풀의 세포독성 성분

  • Choi, Sang-Zin (Natural Products Laboratory, College of Pharmacy, Sung Kyun Kwan University) ;
  • Kwon, Hak-Chul (Natural Products Laboratory, College of Pharmacy, Sung Kyun Kwan University) ;
  • Yi, Jae-Hun (Natural Products Laboratory, College of Pharmacy, Sung Kyun Kwan University) ;
  • Lee, Won-Bin (Natural Products Laboratory, College of Pharmacy, Sung Kyun Kwan University) ;
  • Choi, Sang-Un (Korea Research Institute of Chemical Technology) ;
  • Lee, Kang-Ro (Natural Products Laboratory, College of Pharmacy, Sung Kyun Kwan University)
  • 최상진 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 권학철 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 이재훈 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 이원빈 (성균관대학교 약학대학 천연물 약품화학 연구실) ;
  • 최상운 (한국화학연구소) ;
  • 이강노 (성균관대학교 약학대학 천연물 약품화학 연구실)
  • Published : 2001.03.30
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Abstract

Three alkaloids, (-)-stylopine (I), (+)-chelidonine (II), oxysanguinarine (III) and two triterpenoids, $6{\alpha}-hydroxy-A-neo-germacer-22(29)-en-30-oic\;acid$ (IV) and hop-22(29)-en-30-oic acid (V), were isolated from the methanol extract of of Chelidonium majus var. asiaticum, and their cytotoxicity were tested against five cultured human tumor cell lines.

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