Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
권호 표지

Effects of Dietary Zinc and Iron Levels on Serum Trace Minerals and Obesity Index in High Fat Diet-Induced Obese Rats

고지방 식이를 섭취한 흰쥐의 비만지수 및 식이 아연과 철분 수준에 따른 혈청 미량무기질 함량 변화

  • 김현숙 (숙명여자대학교 식품영양학과) ;
  • 승정자 (숙명여자대학교 식품영양학과)
  • Published : 2001.04.01
Download PDF
⟨ Previous Next ⟩

Abstract

The purpose of this study was to evaluate the obesity index and effect of dietary zinc and iron levels on serum trace minerals status in the high fat diet-induced obese rats. Male Sprague-Dawley rats were randomly assigned to control and high fat diet groups. Ten weeks later, the control and high fat diet group were rearranged into six groups by zinc and iron levels. After 16 wk serum zinc, iron, copper and manganese was analyzed. Obesity index was significantly higher in the group fed high fat diet (20% lard) than that of control group (5% corn oil). Body fat content was 12.10$\pm$4.51g/100g BW in high fat diet group and 7.64$\pm$4.18g/100g BW in control group. So, the obese rats were successfully induced by high fat diet. The trace mineral concentration of obese rats in serum were affected by zinc levels. Serum zinc concentration was increased by dietary zinc overload, whereas the iron, copper and manganese were decreased. Specially the manganese concentration was significantly affected by zinc levels. In both groups, serum trace mineral concentration was not changed significantly by the dietary iron levels. There were positive correlations between zinc, iron and manganese concentration according to dietary zinc and iron levels.

Keywords

References

  1. Kor.J.Nutr. v.25 The prevalence of obesity in children and adolescents Moon,H.N;Hong,S.J;Suh,S.J
  2. Kor.J.Nutr v.27 Clinical and nutritional examination in obese children and adolescents Ahn,H.S;Park,J.K;Lee,D.H;Paik,I.K;Lee,J.H;Lee,Y.J
  3. 국민영양조사보고서 보건복지부
  4. Obesity,fat distribution and cardiovascular disease In Progress in Obese Research Larsson,B;Oomura,Y.(ed.)
  5. Am.J.Clin.Nutr. v.48 Cell-mediated immunity in genetically obese (C57BL/6J ob/ob)mice Chandra,R.K
  6. Am.J.Clin.Nutr. v.48 Zinc in hair and serum of obese individuals in Taiwan Chen,M.D;Lin,P.Y;Lin,W.H;Cheng,V
  7. Rev.Esp.Fisiol. v.38 Changes in the metabolism of iron, copper and zinc in obesity Luque-Diaz,M.J;Dean-Guelbenzu,M;Culebras-Poza,J.M
  8. Acta Paediatr.Jpn. v.39 Serum zinc,copper,and magnesium levels in obese children Yakinci,C;Pac,A;Kucukbay,F.Z;Tayfun,M;Gul,A
  9. J.Nutr. v.111 Non-essential role of dietary factors in the development of diabetes in ob/ob mice Dubuc,P.U
  10. Nippon Suisan Gakkaishi v.58 Relationship between body fat content and body density in cultured red Sea bream Tsuchimoro,M;Miyata,K;Matsuo,S;Osato,S;Kora,H;Misima,T;Tachibana,K
  11. Am.J.Clin Nutr. v.34 The effect of dietary zinc on intestinal copper absorption Fisher,P.W;Giroux,A;L'Abbe,M.R
  12. Arch.Biochem.Biophys. v.46 Effect of excessive dietary zinc in the rat and the interrelationship with copper Van Reen,R
  13. J.Am.Coll.Nurr v.4 Laboratory diagnosis of zinc deficiency Prasad,A.S
  14. Ann Nutr.Metab v.34 Iron deficiency in growing male rats a cause of development of cardiomyopathy Petering,D.H;Stemmer,K.L;Lyman,S;Krezoski,S;Petering,H.G
  15. Ann.Nutr.Metab. v.34 Effect of decreased food consumption during iron deficiency upon growth rate and iron status indicators in the rat Dhur,A;Galan,P;Herberg,S
  16. J.Nutr. v.117 Iron intake influence,essential farty acid and lipid composition of rat plasma and erythrocytes Cunnane,S.C;McAdoo,K.R
  17. J.Nutr. v.120 Manganese,iron and lipid interaction in rats Davis,C.D;Ney,D.M;Greger,J.L
  18. Kor.J.Gerontol v.2 Effect of brown algae component on obese rats induced by a high fat diet Kim,J.I;Choi,J.H
  19. Kor.J.Nutr. v.24 The effect of the levels of dietary zinc and alcohol consumption on lipid metabolism in the rats Kim,M.H;Sung,C.J
  20. J.Nutr. v.97 Copper interference with the intestinal absorption of zinc-65 by rats Van Campen,D,R
  21. Am.J.Clin.Nutr. v.40 Effect of zinc supplementation on copper status in adult man Fisher,P.W;Giroux,A;L'Abbe,M.R
  22. J.Nutr. v.113 Effects of zinc on mucosal copper binding and on the kinetics of copper absorption Fisher,P.W;Giroux,A;L'Abbe,M.R
  23. Am.J.Clin.Nutr. v.34 The effect of dietray zinc on intestinal copper absorption Fisher,P.W;Giroux,A;L'Abbe,M.R
  24. Kor.J.Gerontol. v.4 Effect of dietary iron levels on trace elements in plasma and tissue of rats Yoon,T.H;Kim,H.S
  25. J.Nutr. v.122 Varying levels of manganese and iron affect absorption and gut endogenous losses of manganese by rats Davis,C.D;Wolf,T.L;Greger,J.L