Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
권호 표지

Hepatoprotective and Hypolipidemic Activity of Plantaginis Herba Extracts in Diabetic Model

당뇨성 모델에서 차전초의 간보호 및 지질개선효과

  • Yoon, Soo-Hong (Dept. of Pharmacy,Catholic University of Taegu) ;
  • Ha, Hun (Dept. of Food Science and Technology,Taegu Polytechnic College)
  • 윤수홍 (대구가톨릭대학교 약학과) ;
  • 하헌 (대구산업정보대학 식품가공과)
  • Published : 2001.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

The antihepatic and hypolipidemic activities and total lipid levels of water extract of Plantaginis Herba, used for respiratory and renal disorder in folk medicine, were evaluated in streptozotocin-induced diabetic rats. Diabetes was induced by a single injection of streptozotocin (50 mg/kg, i.ｐ.). Water extract of Plantaginis Herba recovered enzyme activities such as GOT, GPT, ALP and LDH increased by streptozotocin (STZ) treatment. This crude drug also suppressed the enhanced production of lipid in hyperglycemia. These results strongly suggest that Plantaginis Herba be a promising liver-protective and hypolipidemic agent.

Keywords