Archives of Pharmacal Research

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Further Isolation of Peroxynitrite and 1, 1-Diphenyl-2-picrylhy-drazyl Radical Scavenging Isorhamnetin 7-Ο-glucoside from the Leaves of Brassica juncea L.

  • Choi, Jae-Sue (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Jung, Mee-Jung (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Park, Hye-Jin (Faculty of Food Science and Biotechnology, Pukyong National University) ;
  • Chung, Hae-Young (College of Pharmacy, Pusan National University) ;
  • Kang, Sam-Sik (Natural Product Research Institute, Seoul National University)
  • Published : 2002.10.01
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Abstract

From the leaves of Brassica juncea, an radical scavenging isorhamnetin 7-Ο-glucoside on peroxynitrite and 1,1-diphenyl-2-picrylhydrazyl (DPPH) was isolated and characterized based on the spectroscopic evidence. The compound showed the peroxynitrite and DPPH scavenging activities with $IC_{50}$ values of 2.07$\pm$0.17 and 13.3 $\mu$M, respectively. Penicillamine and L-ascorbic acid as positive control exhibited radical scavenging activities with $IC_{50}$ values of 3.17$\pm$0.39 and 12.78 $\mu$M, respectively.

Keywords

References

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