The Journal of Internal Korean Medicine (대한한방내과학회지)
- Volume 24 Issue 2
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- Pages.329-336
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- 2003
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- 1226-9174(pISSN)
Evaluation for Therapeutic Effectiveness of Banwhasashim-tang in Functional Dyspepsia
기능성 소화불량증 환자에 대한 반하사심탕 엑기스제의 임상효과
- Ryu Bong-Ha (Department of 3rd Internal Medicine, College of Oriental Medicine, Kyunghee University) ;
- Ryu Ki-Won (Department of 3rd Internal Medicine, College of Oriental Medicine, Kyunghee University) ;
- Kim Jin-Sung (Department of 3rd Internal Medicine, College of Oriental Medicine, Kyunghee University) ;
- Yoon Sang-Hyub (Department of 3rd Internal Medicine, College of Oriental Medicine, Kyunghee University)
- Published : 2003.06.01
Abstract
Objective : We evaluated the therapeutic effect of Banwhasasimtang dry extract powder on gastrointestinal symptoms and its side effects in patients with functional dyspepsia. Methods : Patients with functional dyspepsia, defined as discomfort in the epigastrium. A total 45 patients participated in this study. Dyspeptic symptoms ratio was obtained by patients, total point of symptom score/total 21 points x 100(%). On each of symptom after 4 weeks administration of Banwhasashim-tang was made by variation of symptom score: If symptoms score of posttreatment is lower than that of pretreatment, it is improved ; Otherwise aggravated, and if there is no change between them, unchangeable. When a full health condition of normal control is assumed 100%, relative health condition of dyspeptic patient could be calculated from 'full health condition-dyspeptic symptoms ratio'. Therefore a whole satisfaction rate on symptom improvement was presented with variation of a relative health condition to dyspepsia between pretreatment and post. Results : Banwhasashimtang significantly improved symptoms in patients. The significance was shown in both all seven items(p<0.01, respectively) and 19.2% (p<0.01) of increase of a whole satisfaction rate on symptom improvement. There is no remarkable side-effect in all laboratory test, excepting 1 case of abdominal pain and another one case of recurred pain of chronic prostatitis. Conclusion : Banwhasashimtang extract provides symptomatic relief in functional dyspepsia and is no remarkable side-effect drug.