Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
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Modulation of Harpagophytum procumbens on ion channels in acutely dissociated periaqueductal gray neurons of rats

천수근이 중심회백질 신경세포에서 이온통로 조절작용에 미치는 영향

  • Shin Min-Chul (Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Chang Hyun-Kyung (Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Jang Mi-Hyeon (Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Kim Chang-Ju (Department of Physiology, College of Medicine, Kyung Hee University) ;
  • Kim Youn-hee (Department of Biochemistry, College of Oriental Medicine, Semyung University) ;
  • Kim Ee-Hwa (Department of Meridian and Acupoint, College of Oriental Medicine, Semyung University)
  • 신민철 (경희대학교 의과대학 생리학교실) ;
  • 장현경 (경희대학교 의과대학 생리학교실) ;
  • 장미현 (경희대학교 의과대학 생리학교실) ;
  • 김창주 (경희대학교 의과대학 생리학교실) ;
  • 김연희 (세명대학교 한의과대학 생화학교실) ;
  • 김이화 (세명대학교 한의과대학 경혈학교실)
  • Published : 2003.12.27
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Abstract

목적:천수근은 염증성 관절염과 염증성 장 질환 등에 사용되어왔다. 천수근이 중심회백질 신경세포에서 하행성 진통작용에 미치는 영향을 연구하였다. 방법: 중심회백질 신경세포를 분리하여 전위고정하에서 nystatin-perforated patch-clamp technique을 시행하였다. 결과: 천수근에 의하여 유발되는 이온전류는 GABA, glycine, 그리고 glutamate 수용체를 모두 활성화시켰다.

Keywords

References

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