한국정밀공학회지 (Journal of the Korean Society for Precision Engineering)

  • 제22권7호
  • /
  • Pages.200-207
  • /
  • 2005
  • /
  • 1225-9071(pISSN)
  • /
  • 2287-8769(eISSN)
한국정밀공학회 (Korean Society for Precision Engineering)
권호 표지

뇌기능 영상에서 인지 수행 능력, 신경 활성화 면적 신경 활성화 크기의 상관관계

Correlation between Cognitive Performance Ability, Neural Activation Area and Neural Activation Intensity in fMRI

  • 발행 : 2005.07.01
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

This study compares two different methods of measuring brain-BOLD activation. By comparing two different methods of measurement i.e., one method calculating the neural activation area (the number of activated voxels), while the other measured the neural activation intensity (the mean intensity of selected activated yokels), this study identified the more precise method of measuring brain activation which results from the completion of a visuospatial task. 16 right-handed male college students (mean age 23.2 years) participated in this study as subjects. Functional brain images were scanned on them using a 3T MRI single-shot EPI method. No correlation was found between the levels of cognitive performance and number of activated yokels in the activated brain areas. However, a significant correlation was found between the levels of cognitive performance and the mean intensity of selected activated yokels in the parietal, frontal, and other areas. In conclusion, the method of mean intensity was considered a better index of brain activity rather than the activated yokels measurement method.

키워드

참고문헌

  1. Cerf-Ducastel, B., Murphy, C., 'FMRI brain activation in response to odors is reduced in primary olfactory areas of elderly subjects,' Brain Research, Vol. 986, pp. 39-53, 2003 https://doi.org/10.1016/S0006-8993(03)03168-8
  2. Persson, J., Sylvester, C.C., Nelson, J.K., Welsh, K.M., Jonides, J., Reuter-Lorenz, P.A., 'Selection requirements during verb generation: differential recruitment in older and younger adults,' NeuroImage, Vol. 23, pp. 1382-1390, 2004 https://doi.org/10.1016/j.neuroimage.2004.08.004
  3. Remy, F., Mirrashed, F., Campbell, B., Richter, W., 'Verbal episodic memory impairment in Alzheimer's disease: a combained structural and functional MRI study,' Neurolmage, In press
  4. Mainero, C., Caramia, F., Pozzilli, C., Pisani, A., Pestalozza, I., Borriello, G., Bozzao, L., Pantano, P., 'fMRI evidence of brain reorganization during attention and memory tasks in multiple sclerosis,' NeuroImage, Vol. 21, pp. 858-867, 2004 https://doi.org/10.1016/j.neuroimage.2003.10.004
  5. Sohn, J.H., Kim, Y.H., Lee, K.H., Park, S.H., 'Brain areas activated by different levels of individual's visuospatial ability: an fMRI study,' Korean Journal of Brain Science and Technology, Vol. 1, No.2, pp. 201-209, 2001
  6. Heun, R., Freymann, N., Granath, D.O., Stracke, C.P., Jessen, F., Barkow, K., Reul, J., 'Differences of cerebral activation between superior and inferior learners during motor sequence encoding and retrieval,' Psychiatry Research Neuroimaging, Vol. 132, pp. 19-32, 2004 https://doi.org/10.1016/j.pscychresns.2004.01.007
  7. Chung, S.C., Sohn, J.H., Kim, I.H., 'The effect of highly concentrated oxygen administration on cerebrum lateralization of young men during visuospatial task,' Journal of the Korean Society of Precision Engineering, Vol. 21, No.8, pp. 180-188, 2004
  8. Mattay, V.S., Callicott, J.H., Bertolino, A., Heaton, I., Frank, J.A., Coppola, R., Berman, K.F., Goldberg, T.E., Weinberger, D.R., 'Effects of Dextroamphetamine on cognitive performance and cortical activation,' NeuroImage, Vol. 12, pp. 268-275, 2000 https://doi.org/10.1006/nimg.2000.0610
  9. Taylor, S.F., Welsh, R.C., Wager, T.D., Phan, K.L., Fitzgerald, K.D., Gehring W.J., 'A functional neuroimaging study of motivation and executive function,' Neurolmage, Vol. 21, pp. 1045-1054, 2004 https://doi.org/10.1016/j.neuroimage.2003.10.032
  10. Lustig, C., Buckner, R.L., 'Preserved Neural Correlates of Priming in Old Age and Dementia,' Neuron, Vol. 42, pp. 865-875, 2004 https://doi.org/10.1016/j.neuron.2004.04.002
  11. Ogawa, S., Tank, D. W., Menon, R., Ellermann, J.M., Kim, S.G., Merkle, H., Ugurbil, K., 'Intrinsic signal changes accompanying sensory stimulation: Functional brain mapping with magnetic resonance imaging,' Proceeding of the National Academy of Sciences of the United States of America, Vol. 89, pp. 5951-5955, 1992 https://doi.org/10.1073/pnas.89.13.5951
  12. Moonen, C.T.W., Bandettini, P.A., 'Functional MRI,' Springer, New York, 1999
  13. Logothetis, N.K., 'The neural basis of the blood-oxygen-Ievel-dependent functional magnetic resonance imaging signal,' Philos. Trans. R. Soc. Lond. B. Biol. Sci., Vol. 29, pp. 1003-1037, 2002 https://doi.org/10.1098/rstb.2002.1114
  14. Lee, S.R., 'Intelligence test 151-Ga Type (High school students - adults),' Jungangjucksung Press, Seoul, Korea, 1982
  15. Lee, S.R., Kim, K.R., 'Aptitude test 251-Ga (High school students - adults),' Jungangjucksung Press, Seoul, Korea, 1985
  16. Park, S.B., 'GATB (General Aptitude Test Battery): academic, job aptitude test type II (for students of middle schools, high schools and universities, and general public),' Jungangjucksung Press, Seoul, Korea, 1985
  17. Chung, S.C., Sohn, J.H., Lee, B., Lee, S.Y., 'Visuospatial cognitive performance, hyperoxia and heart Rate due to oxygen administration,' Journal of the Korean Society of Precision Engineering, Vol. 22, No. 1, pp. 193-198, 2005
  18. Talairach, J., Tournoux, P., 'Co-Planar Stereotaxic Atlas of the Human Brain,' Georg Thieme Verlag, Stuttgart, New York, 1988
  19. Fink, G.R., Marshall, J.C., Weiss, P.H., ZilIes, K., 'The neural basis of vertical and horizontal line bisection judgements: an fMRI study of normal volunteers,' Neuroimage, Vol. 14, No.1, pp. 59-67, 2001 https://doi.org/10.1006/nimg.2001.0819
  20. Ng, V.W., Eslinger, P.J., Williams, S.C., Brammer, M.J., Bullmore, E.T., Andrew, C.M., Suckling, J., Morris, R.G., Benton, A.L., 'Hemispheric preference in visuospatial processing: a complementary approach with fMRI and lesion studies,' Human Brain Mapping, Vol. 10, No.2, pp. 80-86, 2000 https://doi.org/10.1002/(SICI)1097-0193(200006)10:2<80::AID-HBM40>3.0.CO;2-2
  21. Ng, V.W., Bullmore, E.T., de Zubicaray, G.I., Cooper, A., Suckling, J. Williams, S.C., 'Identifying rate-limiting nodes in large-scale cortical networks for visuo spatial processing: an illustration using fMRI,' Journal of Cognitive Neuroscience, Vol. 13, No.4, pp. 538-545, 2001 https://doi.org/10.1162/08989290152001943
  22. Gur, R.C., Alsop, D., Glahn, D., Petty, R., Swanson, C.L., Maldjian, J.A., Turetsky, B. I., Detre, J.A., Gee, J., Gur, R.E., 'An fMRI study of sex differences in regional activation to a verbal and a spatial task,' Brain and Language, Vol. 74, pp. 157-170, 2000 https://doi.org/10.1006/brln.2000.2325
  23. Vitouch, O., Bauer, H., Gittler, G., Leodolter, M., Leodolter, U., 'Cortical activity of good and poor spatial test performances during and spatial and verbal processing studied with slow potential topography,' International Journal of Psychology, Vol. 27, pp. 183-199, 1997 https://doi.org/10.1016/S0167-8760(97)00060-3
  24. Guyton, A.C., 'Textbook of medical physiology,' W.B. Saunders, Philadelphia, 1991