Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

Hepatoprotective Effect of Manual Acupuncture at Sam-hwang Points on $CCl_4$-induced Liver Damage in Rats

$CCl_4$로 유발된 흰쥐의 간손상에 대한 삼황혈(三黃穴) 수기침자극(手技鍼刺戟)의 간기능 보호효과

  • Lee, Hyun (Dept. Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon university) ;
  • Hong, Kwon-Eui (Dept. Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon university) ;
  • Kim, Young-Il (Dept. Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon university) ;
  • Kim, Tae-Han (Dept. Meridian & Acupoint, College of Oriental Medicine, Daejeon university) ;
  • Choi, Hak-Joo (Dept. Meridian & Acupoint, College of Oriental Medicine, Daejeon university) ;
  • Kim, Sun-Jin (Dept. Meridian & Acupoint, College of Oriental Medicine, Daejeon university) ;
  • Yim, Yun-Kyoung (Dept. Meridian & Acupoint, College of Oriental Medicine, Daejeon university)
  • 이현 (대전대학교 한의과대학 침구학교실) ;
  • 홍권의 (대전대학교 한의과대학 침구학교실) ;
  • 김영일 (대전대학교 한의과대학 침구학교실) ;
  • 김태한 (대전대학교 한의과대학 경혈학교실) ;
  • 최학주 (대전대학교 한의과대학 경혈학교실) ;
  • 김선진 (대전대학교 한의과대학 경혈학교실) ;
  • 임윤경 (대전대학교 한의과대학 경혈학교실)
  • Published : 2005.03.27
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Abstract

Objectives : To investigate the hepatoprotective effect of manual acupuncture at Sam-hwang points on hepatotoxicity in $CCl_4$-intoxicated rats. Methods : Rats were injected intraperitoneally with $CCl_4$(1ml/kg) and treated with manual acupuncture at left Sam-hwang points 3 times a week for 10 weeks. A non-acupoint in left Gluteal area was selected as a sham point. Acupuncture was performed by an experienced acupuncture doctor using tonifying manipulation technique. To estimate the effects on hepatotoxici쇼, body weight and liver weight of rats were measured, and biochemical assays(ALT, AST, ALP, Total cholesterol, etc.) and blood cell analysis were performed. Results : Manual acupuncture with tonifying technique at Sam-hwang points reduced liver weight, ALT, AST, ALP activities and total cholesterol in serum significantly compared with control group. In blood cell analysis, WBC and lymphocytes were reduced but neutrophil was increased by manual acupuncture at Sam-hwang points in rats. Conclusions : Manual acupuncture with tonifying technique at Sam-hwang points has an hepatoprotective effect on $CCl_4$-induced liver damage in rats.

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