Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Pharmacognostical Evaluation of Roots of Pygmaeopremna herbacea (Roxb.) Mold.

  • Rastogi, Subha (Pharmacognosy & Ethnopharmacology Division, National Botanical Research Institute) ;
  • Pandey, Madan Mohan (Pharmacognosy & Ethnopharmacology Division, National Botanical Research Institute) ;
  • Kumar, Kaushal (Pharmacognosy & Ethnopharmacology Division, National Botanical Research Institute) ;
  • Rawat, Ajay Kumar Singh (Pharmacognosy & Ethnopharmacology Division, National Botanical Research Institute) ;
  • Pushpangadan, Palpu (Pharmacognosy & Ethnopharmacology Division, National Botanical Research Institute)
  • Published : 2005.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

Pygmaeopremna herbacea (Roxb.) Mold. (Verbenaceae) is a small herb or sometimes an undershrub arising from a perennial rootstock. The dry roots are dark muddy brown in colour having root nodules. Its extensively developed roots are widely used in tribal medicine. They are used as an aphrodisiac and for the treatment of gout, rheumatism and ulcers. This study deals with the detailed pharmacognostical evaluation of the dried roots and root nodules of P. herbacea which includes macro and microscopic studies, determination of physicochemical parameters and chemoprofiling of the extract using HPTLC fingerprint profiles. It was observed that the roots consist of a well developed cortical region consisting of tangentially elongated thin walled parenchymatous cells and contain polygonal stone cells as well as compound starch grains. Also the pith was parenchymatous. The HPTLC fingerprint profile of the methanolic extract showed the presence of seven major bands. Such an analysis may thus be utilized in identifying P. herbacea and in differenciating it from other species which are similar to it or are used as its adultrants/substitutes under the same vernacular name of Bharangi.

Keywords

References

  1. Anonymous, Indian Pharmacopoeia, 2nd Edn. Government of India, New Delhi. (1966)
  2. Anonymous, The Wealth of India. A Dictionary of Indian Raw Material and Industrial Products (CSIR, New Delhi) 8, 239 (1950)
  3. Anonymous, The Useful Plants of India, NISCOM (CSIR, New Delhi), 489 (1986)
  4. Goel, A.K., Sahoo, A.K., and Mudgal, V.A., Contribution to the ethnobotany of Santhal Pargana. Bihar Bot. Surv. India, Howrah (1984)
  5. Gopalan, S., Krishnamurthy, R., and Narayanan, C., Structure of sirutekkone, a diterpenoid from Premna herbacea. Phytochem. 27, 2249-2250 (1988) https://doi.org/10.1016/0031-9422(88)80135-3
  6. Johansen, D.A., Plant Microtechnique, 1st Edn. Mc Graw Hill Book Co. Inc, New York and London, 1940
  7. Kokate, C.K., Practical Pharmacognosy. Vallabh Prakashan, Delhi, India, pp. 15-29 (1986)
  8. Maheshwari, J.K., Singh, K.K., and Saha, S., Ethnomedicinal uses of plants by Tharus in Kheri district U. P. Bull. Medicoethnobot. Res. 1, 318-337 (1980)
  9. Narayanan, N., Thirugnanasambantham, P., Viswanathan, S., Reddy, M.K., Vijayasekaran, V., and Sukumar, E., Antipyretic, antinociceptive and anti-inflammatory activity of Premna herbacea roots. Fitoterapia 71, 147-153 (2000) https://doi.org/10.1016/S0367-326X(99)00132-X
  10. Narayanan, N., Thirugnanasambantham, P., Viswanathan, S., Sukumar, E., and Jeyaraman, P., Pharmacognostical studies on the roots of Clerodendrum serratum. Pharmaceutical Biol. 40, 362-368 (2002) https://doi.org/10.1076/phbi.40.5.362.8454
  11. Nayar, R.C., Yoganarasimhan, S.N., and Subramanyam, K, Pharmacognosy of a local market sample of Bharangi- Pygmaeopremna herbacea (Roxb.) Moldenke. Indian J. Pharm. 38, 39-42 (1976)
  12. Prakash, A. and Singh, K.K., Observations on some high valued ethnomedicinal plants among the tribals of Uttar Pradesh. J. Med Arom. Plant Sci., 22-23, 519-521 (2000-2001)
  13. Prakash, A. and Singh, K.K., Observations on some threatened plants and their conservation in Rajaji National Park in Uttaranchal, India. J Eco. Tax. Bot., 25, 363-366 (2001)
  14. Qingchang, M., Naijue, Z., and Weixin, C.A diterpenoid with a new carbon skeleton from Pygmaeopremna herbacea. Phytochem. 27, 1151-1152 (1988a) https://doi.org/10.1016/0031-9422(88)80292-9
  15. Qingchang, M. and Weixin, C, Pygmaeoherin: novel coumarin from Pygmaeopremna herbacea. Planta Med. 54, 48-49 (1988b) https://doi.org/10.1055/s-2006-962333
  16. Saxena, H.O., Observations on the ethnobotany of Madhya Pradesh. Bull. Bot. Surv. India, 28, 149-156 (1986)
  17. Weixin, C., Two novel diterpenoids from Pygmaeopremna herbacea. J Nat. Prod 52, 581-587 (1989) https://doi.org/10.1021/np50063a018