Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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The Chemical Constituents and their Antioxidant Activity of the Stem of Rhododendron mucronulatum

  • Lee, Jin-Hoon (College of Pharmacy, Kangwon National University) ;
  • Jeon, Wan-Joo (Department of Pharmacology, College of Medicine, Kangwon National University) ;
  • Yoo, Eun-Sook (Department of Pharmacology, College of Medicine, Cheju National University) ;
  • Kim, Chang-Min (College of Pharmacy, Kangwon National University) ;
  • Kwon, Yong-Soo (College of Pharmacy, Kangwon National University)
  • Published : 2005.06.01
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Abstract

From the n-BuOH soluble traction of the 70% aqueous acetone extract of Rhododendron mucronulatum stem, twelve compounds were isolated. On the basis of spectral data, they were identified as scopoletin (1), (+)-taxifolin (2), quercetin (3), (-)-catechin (4), (+)-epicatechin (5), scopolin (6), lyoniside (7), ssioriside (8), fraxin (9), $(+)-lyoniresinol-3{\alpha}-O-{\beta}-D-glucopyranoside$ (10), $(+)-taxifolin-3-O-{\alpha}-L-arabinopyranoside$ (11), and astragalin (12), respectively. All isolated compounds were tested antioxidant activity against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical. Compounds 2 and 3 showed the potent antioxidant activity, and compounds 5, 8, and 11 showed moderate activity.

Keywords

References

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