Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Hypoglycemic Effect of Paecilomyces japonica in NIDDM Patients

누에 동충하초(Paecilomyces japonica) 섭취가 당뇨환자의 혈당저하능에 미치는 영향

  • Kim, Hyun-Sook (Institute of Korea Nutritional Science, Kangwon National University) ;
  • Choe, Myeon (Dept. of Animal Food Science, Kangwon National University)
  • 김현숙 (강원대학교 한국영양과학연구소) ;
  • 최면 (강원대학교 축산식품과학과)
  • Published : 2005.07.01
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Abstract

The purpose of this study is to investigate tile effects of the Paecilomyces japonica on blood glucose in non-insulin dependent diabetes mellitus volunteers. During the 3 months of the experimental period, freeze-dried powder of Paecilomyces japonica (2 g/meal) was given to the subjects right before each meal. Paecilomyces japonica caused a significant decrease of $27.5\%\;and\;35.5\%$ in fasting and postprandial blood glucose levels, respectively. There were significant reductions of $28.5\%\;and\;33.5\%$ in fasting and postprandial blood glucose levels of the male subjects, respectively Paecilomyces japonica also significantly decreased in fasting and postprandial blood glucose levels of $26.1\%\;and\;37.3\%$ in female patients after treatment. This study shows that Paecilomyces japonica supplementation significantly lowered the fasting and postprandial glucose levels in NIDDM patients. These effects presumably contribute to the hypoglycemic activity.

누에 동충하초(Paecilomyces japonica) 섭취 후 공복혈당은 $27.5\%$, 식후혈당은 $35.5\%$로 감소하였으며, 복용 중단 2주 후에도 실험전 혈당 수준과 비교할 때 각각 $18.2\%,\;27.2\%$ 저하된 상태를 유지하고 있었다. 이는 복용할 때 뿐 아니라 복용 후 어느 정도 기간까지는 지속적으로 혈당 강하 효과가 있음을 의미한다. 남자 당뇨병 환자의 공복혈당은 $28.5\%$, 식후혈당은 $33.5\%$ 감소되었고, 여자 환자의 공복혈당은 $26.1\%$, 식후혈당은 $37.3\%$ 감소되었다. 이러한 결과로 볼 때 누에 동충하초는 인슬린비의존형 성인 당뇨병 환자의 혈당을 감소시키는데 유용한 기능성 식품으로 활용될 수 있을 것으로 판단된다.

Keywords

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