Advances in Traditional Medicine

Kyung Hee Oriental Medicine Research Center (경희대학교 융합한의과학연구소)
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Radiation effects to acupuncture in mice embryos

  • Tano Kaori (Department of Acupuncture Moxibustion, Faculty of Acupuncture Moxibustion, Suzuka University of Medical Science) ;
  • Itokawa Yuka (Graduate School of Health Science, Suzuka University of Medical Science) ;
  • Maenaka Toshihiro (Graduate School of Health Science, Suzuka University of Medical Science) ;
  • Sakazaki Takahiko (Graduate School of Health Science, Suzuka University of Medical Science) ;
  • Yamashita Takenori (Graduate School of Health Science, Suzuka University of Medical Science) ;
  • Nakamura Takashi (Graduate School of Health Science, Suzuka University of Medical Science) ;
  • Cho Kwang-Ho (Gyeongdo provincial college) ;
  • Choi Jung-Sook (Department of Radiological Science, Catholic University of Deagu, College of Heallth Science) ;
  • Ahn Kyoo-Seok (Department of Pathology, College of Oriental medicine, Institute of Oriental Medicine, Kyung Hee University) ;
  • Ishida Torao (Department of Acupuncture Moxibustion, Faculty of Acupuncture Moxibustion, Suzuka University of Medical Science) ;
  • Gu Yeun-Hwa (Graduate School of Health Science, Suzuka University of Medical Science)
  • Published : 2006.09.01
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Abstract

We examined the radioprotection effects of acupoint (acupuncture point) stimulation during organogenesis stages of ICR mice. Pregnant mice received 1.5 Gy whole body X-irradiation on day 8 of gestation, which is the early stage of organogenesis. The embryonic death rate and teratogenesis rate by radiation were examined. Electroacupuncture to the leg acupoints and/ or transcutaneous stimulation to the back acupoints on the pregnant mice showed no protective effect against irradiation on embryonic or fetal death rate. On the contrary, the strong stimulation resulted in increase in the mortality after irradiation rather than protection. However acupoint stimulation to the pregnant mice never showed harmful effects by itself on embryos. It tended to reduce the skeletal malformations induced by X-ray irradiation. We suspect that acupoint stimulation removed the cells injured by irradiation during embryonic development, resulting in an increase in embryonic death rate and reduction in skeletal anomalies.

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References

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