Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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Effects of injectable β-carotene on mastitis in dairy cows

젖소 유방염에 대한 주사용 β-carotene의 효과

  • Nam, Hyang-Mi (National Veterinary Research and Quarantine Service) ;
  • Moon, Jin-San (National Veterinary Research and Quarantine Service) ;
  • Joo, Yi-Seok (National Veterinary Research and Quarantine Service) ;
  • Park, Yong-Ho (College of Veterinary Medicine, Seoul National University) ;
  • Han, Hong-ryul (College of Veterinary Medicine, Seoul National University)
  • 남향미 (국립수의과학검역원) ;
  • 문진산 (국립수의과학검역원) ;
  • 주이석 (국립수의과학검역원) ;
  • 박용호 (서울대학교 수의과대학) ;
  • 한홍율 (서울대학교 수의과대학)
  • Accepted : 2006.06.14
  • Published : 2006.06.30
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Abstract

To determine the effects of ${\beta}$-carotene on the control of mastitis in dairy cows during the dry period, 38 dairy cows (18 mastitic cows and 20 healthy cows) were administered with 5 ml of ${\beta}$-carotene (30 mg/ml) intramuscularly twice (4 week intervals). Blood samples were taken from the cows before the injection and two weeks after the second injection, respectively, and were measured for the proportion of lymphocyte subpopulations and lymphocyte proliferation responses. With ${\beta}$-carotene injection, the proportion of cells expressing BoCD2, BoCD4 and B and N cells increased in healthy cows. In the presence of mitogens, lymphocytes from healthy cows showed significantly higher proliferation responses after ${\beta}$-carotene injection than before (p < 0.05), The somatic cell counts in ${\beta}$-carotene injected group decreased from 1,001,00 cells/ml at dry off to 647,000 cell/ml and 447 cells/ml at the stage of first and second weeks after calving, respectively (p < 0,05), This study indicated that ${\beta}$-carotene as a nonspecific immunostimulator could have a definite role for the prevention of intramammary infections in dairy cows at dry period.

Keywords

References

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