Anti-aging Effect of Amino Acid Complex on the Skin

Amino Acid Complex의 항노화 작용

  • 김기호 ((주)바이오랜드 생명공학연구소) ;
  • 김기수 ((주)바이오랜드 생명공학연구소) ;
  • 김영희 ((주)바이오랜드 생명공학연구소) ;
  • 고강일 ((주)바이오랜드 생명공학연구소) ;
  • 박선희 ((주)바이오랜드 생명공학연구소) ;
  • 김진국 ((주)바이오랜드 생명공학연구소) ;
  • 최현진 ((주)바이오랜드 생명공학연구소) ;
  • 고수연 ((주)바이오랜드 생명공학연구소) ;
  • 배윤주 ((주)엘리드 피부과학연구소) ;
  • 김용민 ((주)바이오랜드 생명공학연구소)
  • Published : 2006.06.30

Abstract

Amino acid complex was made with the composition of amino acids quite similar to that of stratum corneum on the skin. In order to evaluate the efficacy of amino acid complex on the skin as an active cosmetic ingredient, we measured cytotoxicity. TIMP-1 expression, moisturizing effect and the amount of horny substance. In cytotoxicity assay, amino acid complex did not show any cytotoxicity. In moisturizing effect test using corneometer, it showed very good moisturizing effect. In TIMP-1 mRNA assay using RT-PCR, moo acid complex showed the increase of TIMP-1 expression, suggesting that amino acid complex have anti-wrinkle effect. Therefore, amino acid complex may be useful as an active ingredient for anti-aging.

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