Paratuberculosis in mouflon (ovis musimon) : A case report

무플론 요네병 발생 사례

  • Bae, You-Chan (National Veterinary Research and Quarantine Service (NVRQS)) ;
  • Kim, Ha-Young (National Veterinary Research and Quarantine Service (NVRQS)) ;
  • Kim, Heui-Jin (National Veterinary Research and Quarantine Service (NVRQS)) ;
  • Yoon, Soon-Seek (National Veterinary Research and Quarantine Service (NVRQS)) ;
  • Park, Jung-Won (National Veterinary Research and Quarantine Service (NVRQS)) ;
  • Jean, Yong-Hwa (National Veterinary Research and Quarantine Service (NVRQS)) ;
  • Cho, Kyoung-Oh (College of Veterinary Medicine, Jeonnam National University) ;
  • Kang, Mun-Il (College of Veterinary Medicine, Jeonnam National University)
  • Accepted : 2006.09.14
  • Published : 2006.09.30

Abstract

A 2-years-old female domesticated mouflon with a clinical history of chronic diarrhea and emaciation was submitted to NVRQS. Grossly, there were severe thickening of small intestine wall and enlargement of mesenteric lymph nodes. Microscopically, severe granulomatous inflammation was found in small and large intestine, mesenteric lymph nodes, spleen and liver. By Ziehl-Neelsen stain, innumerable acid-fast rod bacteria were found in the cytoplasm of epitheloid and Langhans type giant cells present in these organs. By PCR assay with primer pair specific for Mycobacterium avium subspecies paratuberculosis(IS 900) with small intestine sample, strong positive reaction was detected, although the organism was not isolated from this organ. Based on the results of histopathology and PCR, we concluded that the case was a typical paratuberculosis in mouflon. As far as we know, this is the first case report of paratuberculosis in mouflon Korea.

Keywords

References

  1. 배종희, 진영화. Sika deer의 paratuberculosis 자연발생 예에 관한 병리학적 관찰. 대한수의학회지. 1993, 33, 673-678
  2. 황의경, 진영화, 손현주, 문운경, 김재훈, 배유찬, 박중원, 최상호, 윤상보. 한우 요네병 발생 증례 보고. 농업과학논문집. 1997, 39, 33-41
  3. Boever WJ, Peters D. Paratuberculosis in two herds of exotic sheep. J Am Vet Med Assoc 1974, 165, 822
  4. Buergelt CD, Hall C, Mcentef K, Duncan JR. Pathological evaluation of paratuberculosis in naturally infected cattle. Vet Pathol 1978, 15, 196-207 https://doi.org/10.1177/030098587801500206
  5. Buergelt CD, Layton AW, Ginn PE, Taylor M, King JM, Habecker PL, Mauldin E, Whitlock R, Rossiter C, Collins MT. The pathology of spontaneous paratuberculosis in the North American Bison (Bison bison). Vet Pathol 2000, 37, 428-438 https://doi.org/10.1354/vp.37-5-428
  6. Carrigan MJ, Seaman JT. The pathology of Johne's disease in sheep. Aust Vet J 1990, 67, 47-50 https://doi.org/10.1111/j.1751-0813.1990.tb07693.x
  7. Dukes TW, Glover GJ, Brooks BW, Duncan JR, Swendrowski M. Paratuberculosis in saiga antelope (Saiga tatarica) and experimental transmission to domestic sheep. J Wildlife Disease 1992, 28, 161-170 https://doi.org/10.7589/0090-3558-28.2.161
  8. Hines SA, Buergelt CD, Wilson JH, Bliss EL. Disseminated Mycobacterium paratuberculosis infection in a cow. J Am Vet Med Assoc 1987, 190, 681-683
  9. Huntley JEJ, Whitlock RH, Bannantine JP, Stabel JR. Comparision of diagnostic detection methods for Mycobacterium avium subsp. paratuberculosis in North American bison. Vet Pathol 2005, 42, 42-51 https://doi.org/10.1354/vp.42-1-42
  10. Paolicchi FA, Vagnozzi A, Morsella CG, Verna AE, Massone AR, Portiansky EL, Gimeno EJ. Paratuberculosis in red deer (cervus elaphus): an immunohisto-chemical study. J Vet Med B 2001, 48, 313-320 https://doi.org/10.1046/j.1439-0450.2001.00458.x
  11. Tafti AK, Rashidi K. The pathology of goat paratuberculosis: gross and histopathological lesions in the intestines and mesenteric lymph nodes. J Vet Med B 2000, 47, 487-495 https://doi.org/10.1046/j.1439-0450.2000.00375.x
  12. Williams ES, Snyder SP, Martin KL. Pathology of spontaneous and experimental infection of North American wild ruminants with Mycobacterium paratuberculosis. Vet Pathol 1983, 20, 274-291 https://doi.org/10.1177/030098588302000304
  13. William ES, Spraker TR. Paratuberculosis (Johne's disease) in bighorn sheep and a rocky mountain goat in Colorado. J Wildlife Dis 1979, 15, 221-227 https://doi.org/10.7589/0090-3558-15.2.221