The Korea Journal of Herbology (대한본초학회지)
- Volume 22 Issue 4
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- Pages.279-286
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- 2007
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Effects of Cynanchum spp. on the hyperlipidemia in rats induced by Triton WR-1339
국산 및 중국산 백수오(白首烏)의 Triton WR-1339 유발 고지혈증(高脂血症) 흰쥐에 대한 효능 연구
- Choi, Ho-Young (College of Oriental Medicine, Kyunghee University) ;
- Ham, In-Hye (College of Oriental Medicine, Kyunghee University) ;
- Lee, Ju-Yeong (College of Oriental Medicine, Kyunghee University) ;
- Yoon, Ye-Jin (College of Oriental Medicine, Kyunghee University) ;
- Yang, Gab-Sik (College of Oriental Medicine, Kyunghee University) ;
- Tae, Jin (College of Oriental Medicine, Kyunghee University) ;
- Bu, Young-Min (College of Oriental Medicine, Kyunghee University) ;
- Kim, Ho-Cheol (College of Oriental Medicine, Kyunghee University)
- 최호영 (경희대학교 한의과대학) ;
- 함인혜 (경희대학교 한의과대학) ;
- 이주영 (경희대학교 한의과대학) ;
- 윤예진 (경희대학교 한의과대학) ;
- 양갑식 (경희대학교 한의과대학) ;
- 태진 (경희대학교 한의과대학) ;
- 부영민 (경희대학교 한의과대학) ;
- 김호철 (경희대학교 한의과대학)
- Published : 2007.12.31
Abstract
Objective : In order to compare of hyperlipidemia effect of C. wilfordii, C. auriculatum in korea and C. auriculatum in China, it was performed on the hyperlipidemia in rats induced by Triton WR-1339. Method : The 70% MeOH extracts from dried root of C. wilfordii and C. auriculatum in korea and C. auriculatum in china were fractionated into H2O layer and CHCl3 layer. The level of total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, AST and ALT in serum were used to observe the effectiveness of C. wilfordii korean C. auriculatum and chinese C. auriculatum. Results : In the hyperlipidemic rats induced by Triton WR-1339, C. wilfordii and korean C. auriculatum significantly decreased total cholesterol, triglyceride, otherwise significantly increased HDL. And C. wilfordii and chinese C. auriculatum significantly decreased AST and ALT. Conclusion : This study indicate that C. wilfordii korean C. auriculatum and chinese C. auriculatum were effective in the hyperlipidemic rats induced by Triton WR-1339. According to the results, C. wilfordii korean C. auriculatum and chinese C. auriculatum need to considered for the application in hyperlipidemia.