Abstract
A 2-year-old spayed female ferret with the clinical signs of diarrhea and anorexia for about 8 days was presented to Hansung animal hospital. The diarrhea was black and paste form. Three palpable abdominal masses were detected in physical examination. By cytologic examination using fine need aspiration, the patient was tentatively diagnosed as lymphoma. Chemotherapy was started with prednisone, vincristine and cyclophosphamide. However, the client requested stopping the therapy at day 18 and the ferret was euthanized. Autopsy was performed and the masses were confirmed as lymphoma by histopathology. Microscopically, the mass consisted of unencapsulated and infiltrative neoplasm consisted of closely packed monomorphic round cells and also ininvasive lesions observed in duodenum. On the higher magnification, pleomorphic neoplastic cells with distinct cell border and abundant eosinophilic cytoplasm were observed. Finally, the ferret diagnosed as alimentary lymphoma.
