The Case-Control Study on Complete Blood Count as a Risk Factor of Stroke

뇌졸중 위험지표로서의 일반혈액검사 소견에 대한 환자;대조군 연구

  • Lee, Hyon-Ui (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kang, Kyung-Won (Dept. of Medical Research, Korea Institute of Oriental Medicine) ;
  • Yu, Byeong-Chan (Dept. of Medical Research, Korea Institute of Oriental Medicine) ;
  • Bang, Ok-Sun (Dept. of Medical Research, Korea Institute of Oriental Medicine) ;
  • Baek, Kyung-Min (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol, In-Chan (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Yoon-Sik (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 이현의 (대전대학교부속한방병원 심계내과학교실) ;
  • 강경원 (한국한의학연구원 의료연구부) ;
  • 유병찬 (한국한의학연구원 의료연구부) ;
  • 방옥선 (한국한의학연구원 의료연구부) ;
  • 백경민 (대전대학교부속한방병원 심계내과학교실) ;
  • 설인찬 (대전대학교부속한방병원 심계내과학교실) ;
  • 김윤식 (대전대학교부속한방병원 심계내과학교실)
  • Published : 2007.12.30

Abstract

Objective : Stroke is one of the most common causes of death in Korea. This study was done to evaluate the association of complete blood count (CBC) with the risk of hemorrhagic stroke and ischemic stroke. Methods : In 217-case patients with ischemic stroke or hemorrhagic stroke and 146 healthy control subjects without stroke, hypertension, diabetes mellitus, hyperlipidemia, or ischemic heart disease and 160 controls without ischemic stroke or hemorrhagic stroke, we tested and compared white blood cell count (WBC), red blood cell count (RBC), hemoglobin (Hgb), hematocrit (Hct) and platelet. These data were statically analyzed by general linear models and binary logistic regression analysis to get each adjusted odds ratio. Results :The level of WBC was significantly higher in all cases. The level of RBC, Hct and Hgb was significantly lower in patients of ischemic stroke. The level of platelet was significantly higher in patients of ischemic stroke. Conclusion : These results suggest high WBC may be a risk factor of hemorrhagic stroke and ischemic stroke and low RBC, low Hct, low Hgb and high platelet may be risk factors of ischemic stroke in Koreans.

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