Journal of the Korean Society of Food Science and Nutrition (한국식품영양과학회지)

The Korean Society of Food Science and Nutrition (한국식품영양과학회)
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Weight Reduction and Lipid Lowering Effects of Sea Tangle Added Korean Cabbage Kimchi

다시마 첨가 배추김치의 체중 감량 및 지질 저하 효과

  • Ku, Hwa-Suk (Dept. of Food Science & Nutrition, and Kimchi Research Institute, Pusan National University) ;
  • Noh, Jeong-Sook (Dept. of Food Science & Nutrition, and Kimchi Research Institute, Pusan National University) ;
  • Yun, Ye-Rang (Dept. of Food Science & Nutrition, and Kimchi Research Institute, Pusan National University) ;
  • Kim, Hyun-Ju (Dept. of Food Science & Nutrition, and Kimchi Research Institute, Pusan National University) ;
  • Kwon, Myung-Ja (Dept. of Food Science & Nutrition, and Kimchi Research Institute, Pusan National University) ;
  • Cheigh, Hong-Sik (Busan Metropolitan City Institute of Health & Environment) ;
  • Song, Yeong-Ok (Dept. of Food Science & Nutrition, and Kimchi Research Institute, Pusan National University)
  • 구화숙 (부산대학교 식품영양학과 및 김치연구소) ;
  • 노정숙 (부산대학교 식품영양학과 및 김치연구소) ;
  • 윤예랑 (부산대학교 식품영양학과 및 김치연구소) ;
  • 김현주 (부산대학교 식품영양학과 및 김치연구소) ;
  • 권명자 (부산대학교 식품영양학과 및 김치연구소) ;
  • 최홍식 (부산시 보건환경연구원) ;
  • 송영옥 (부산대학교 식품영양학과 및 김치연구소)
  • Published : 2007.09.30
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Abstract

A recipe for diet kimchi containing 20% of sea tangle to Korean cabbage kimchi (SK) was developed for weight reduction purpose. The fermentation process of SK showed typical Lactobacillus sp. growth pattern like other kimchis. The effects of SK on weight reduction was studied in high fat diet (HFD) fed rats (n=40). Diet groups used for the animal study were HFD, HFD supplemented either with Korean cabbage kimchi used as experimental control (HCK), or with SK (HSK), or with J-kimchi (JK) which was purchased at market (FJK). The effect of kimchi on preventing obesity in rat fed HFD was found to be obvious by means of reducing visceral fat contents and improving serum lipid profiles through enhancing the lipid excretion in the feces (p<0.05). Leptin concentration of rat was significantly decreased by kimchi consumption (p<0.05). This result can be interpreted that adipocytes in these animals were fewer than that of HFD group. The plasma bililubin concentration was lower in kimchi group than HFD, meaning that returning bile from ileum to the liver was reduced. When the observe beneficial effects of kimchi on preventing obesity were compared among kimchi groups, SK only reduced the relative visceral fat contents significantly than other kimchi groups (p<0.05). Besides this, other parameters such as plasma lipid profiles, feces lipids, leptin, and bililubin concentration were not significantly different, even though the most beneficial effect on these parameters was observed from SK. In conclusion, long term consumption of SK seems to have a beneficial effect on the prevention of obesity through enhancing the excretion of lipids in the feces. The dietary fiber content of SK was increased by 7% compared to CK when 20% of sea tangle was added.

체중감량 효과가 있는 기능성 배추김치를 개발하기 위하여 기호도가 우수하고 섬유소가 풍부하여 지질저하 기능성 물질을 함유한 다시마를 첨가한 해조첨가 배추맛김치(이하 해조김치) 레시피를 개발하고, 잘 숙성된 해조김치를 고지방식이를 섭취한 쥐에게 공급하여 지질저하 및 비만억제 효과를 살펴보았다. 배추김치에 다시마를 20% 정도 첨가하였을 때(해조김치) 종합적인 관능평가가 가장 우수하였다. 해조김치의 숙성 특성은 일반 김치와 같이 전형적인 발효양상을 보였다. 해조김치의 비만억제 효과를 살펴보기 위하여 20% 고지방식이에 동결 건조한 김치 10%를 첨가하여 쥐를 8주간 사육하였다. 실험군으로는 고지방식이군, 대조김치군, 해조김치군 그리고 시판용 공장김치를 첨가한 J-김치군으로 하였다. 식이 섭취량, 식이효율은 각 군간에 유의적인 차이가 없었다. 김치첨가에 의한 효과를 고지방식이군과 비교하여 보았을 때 상대적인 내장 지방량은 해조김치군(-17%), J-김치군(-11%) 그리고 대조김치군(-9%) 순으로 감소하였다(p<0.05). 혈청 leptin 농도는 해조김치군(-59%)에서 감소하였는데(p<0.05), 이는 해조김치군의 지방세포의 수가 대조군에 비해 감소함을 의미한다. 혈청 빌리루빈 농도는 해조김치군(-24%)에서 감소하였다(p<0.05). 혈청 중성지방과 콜레스테롤 농도는 고지방군에 비해 각각 해조김치군(-51%와 -21%), J-김치군(-40%, -23%) 그리고 대조김치군(-39%, -13%) 유의적으로 낮았다(p<0.05). 분변의 중성지방과 콜레스테롤 농도는 각각 해조김치군(49%와 71%), 대조김치군(36%, 61%), 그리고 J-김치군(32%, 65%)에서 증가하였다. 김치 종류에 따른 비만억제 효과를 살펴보았을 때 해조김치의 상대적인 내장 지방량은 다른 김치군에 비해 유의적으로 낮았고(p<0.05), 렙틴, 혈청지질, 분변지질 및 빌리루빈의 농도는 김치군간 유의적인 차이는 없었으나, 해조김치군의 비만억제 효과가 가장 높았다. 이러한 결과를 살펴보면, 일반 김치에 비해 해조김치를 섭취하면 체중 감량의 효과가 있을 것으로 생각된다. 이러한 해조김치의 비만 억제 기전은 다시마 첨가에 의해 식이섬유소의 함량이 7% 증가함으로써 소장에서 식이지방 흡수를 방해하여 혈청 중성지방의 농도를 낮추고 이로 인하여 지방세포로 중성지질의 이동이 낮아져 복부지방 축적이 억제되었기 때문으로 생각된다.

Keywords

References

  1. Korea Health Industry Development Institute in Ministry of Health and Welfare. 2006. Report on 2005 National Health and Nutrition Survey. Seoul, Korea
  2. Witteman JCM, Willet WC, Stampfer MJ, Colditz GA, Sacks FM, Speizer FE, Rosner B, Hennekens CH. 1989. A prospective study of nutritional factors and hypertension among US women. Circulation 80: 1320-1327 https://doi.org/10.1161/01.CIR.80.5.1320
  3. Westlund K, Nicolaysen R. 1972. Ten-year mortality related to serum cholesterol: a followup of 3751 men aged 40-49. Scand J Clin Lab Invest 30: 1-24 https://doi.org/10.3109/00365517209081082
  4. Ceschi M, Gutzwiller F, Moch H, Eichholzer M, Probst- Hensch NM. 2007. Epidemiology and pathophysiology of obesity as cause of cancer. Swiss Med Wkly 27: 50-56
  5. Grundy SM. 1998. Multifactorial causation of obesity: implications for prevention. Am J Clin Nutr 67: 563S-572S https://doi.org/10.1093/ajcn/67.3.563S
  6. Albu J, Allison D, Boozer CN, Heymsfield S, Kissileff H, Kretser A, Krumhar K, Leibel R, Nonas C, Pi-Sunyer X, Vanltallie T, Wedral E. 1997. Obesity solutions: report of a meeting. Nutr Rev 55: 150-156 https://doi.org/10.1111/j.1753-4887.1997.tb06469.x
  7. Considine RV, Sinha MK, Heiman ML. 1996. Serum immunoreactive leptin concentrations in normal weight and obese humans. N Engl J Med 334: 292-295 https://doi.org/10.1056/NEJM199602013340503
  8. Mistry AM, Swick AG, Romos DR. 1997. Leptin rapidly lowers food intake and elevates metabolic rats in lean ob/ob mice. J Nutr 127: 2065-2072
  9. Steppan CM, Crawford DT, Chidsey-Frink KL, Ke H, Swick AG. 2000. Leptin is a potent stimulator of bone growth in ob/ob mice. Regyl Pept 92: 73-78 https://doi.org/10.1016/S0167-0115(00)00152-X
  10. O'Donnell CP, Tankersley CG, Polotsky VP, Schwartz AR, Smith PL. 2000. Leptin, obesity and respiratory function. Physiol 119: 163-170
  11. Matheny LH, Michael NM, Scarpace PJ. 1997. Leptin gene expression increases with age independent of increasing adiposity in rats. Diabetes 46: 2035-2039 https://doi.org/10.2337/diabetes.46.12.2035
  12. Colombo C, Cutson J, Yamauchi T. 2002. Transplantation of adipose tissue lacking leptin is unable to reverse the metabolic abnormalities associated with lipoatrophy. Diabetes 51: 2727-2733 https://doi.org/10.2337/diabetes.51.9.2727
  13. Miaianu L, Zhu JH, Rogers NL. 2000. In vitro determine the relationship between body fat and serum leptin levels and degree of adiposity in adult rats. Diabetes 49: 313-320
  14. Choi SH, Kim HJ, Kwon MJ, Baek YH, Song YO. 2001. The effects of kimchi pill supplementation on plasma lipid concentration in healthy people. J Korean Soc Food Sci Nutr 30: 913-920
  15. Jeon HN, Kwon MJ, Song YO. 2002. Effect of kimchi solvent fractions on accumulation of lipids in heart, kidney and lung of rabbit fed high cholesterol diet. J Korean Soc Food Sci Nutr 31: 814-818 https://doi.org/10.3746/jkfn.2002.31.5.814
  16. Jeon HN, Kim HJ, Song YO. 2003. Effects of kimchi solvent fractions on anti-oxidative enzyme activities of heart, kidney and lung of rabbit fed a high cholesterol diet. J Korean Soc Food Sci Nutr 32: 250-255 https://doi.org/10.3746/jkfn.2003.32.2.250
  17. Cho EJ, Rhee SH, Kang KS, Park KY. 1999. In vitro anticancer effect of chinese cabbage kimchi fractions. J Korean Soc Food Sci Nutr 28: 1326-1332
  18. Sheo HJ, Seo YS. 2003. The antibacterial action of chinese cabbage kimchi juice on Staphylococcus aureus, Salmonella enteritidis, Vibrio parahaemolyticus and Enterobacter cloacae. J Korean Soc Food Sci Nutr 32: 1351-1356 https://doi.org/10.3746/jkfn.2003.32.8.1351
  19. Baek YH, Kwak JR, Kim SJ, Han SS, Song YO. 2001. Effects of kimchi supplementation and/or exercise training on body composition and plasma lipids in obese middle school girls. J Korean Soc Food Sci Nutr 30: 906-912
  20. Kim MJ, Kwon MJ, Song YO, Lee EK, Youn HJ, Song YS. 1997. The effects of kimchi on hematological and immunological parameters in vivo and in vitro. J Korean Soc Food Sci Nutr 26: 1-7
  21. Kwon MJ. 1998. Antiatherogenic effect of Baechu kimchi. PhD Dissertation. Pusan National University
  22. Kim HJ. 2004. The preventive and theraputic effects of 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid, an active principle in kimchi, on atherosclerosis in rabbits. PhD Dissertation. Pusan National University
  23. de Roos NM, Katan MB. 2000. Effects of probiotic bacteria on diarrhea, lipid metabolism, and carcinogenesis: a review of papers published between 1988 and 1998. Am J Clin Nutr 71: 405-411 https://doi.org/10.1093/ajcn/71.2.405
  24. Kim HJ, Kwon MJ, Seo JM, Kim JK, Song SH, Suh HS, Song YO. 2004. The effect of 3-(4'-hydroxyl-3',5'-dimethoxyphenyl)propionic acid in Chinese cabbage kimchi on lowering hypercholesterolemia. J Korean Soc Food Sci Nutr 33: 52-58 https://doi.org/10.3746/jkfn.2004.33.1.052
  25. Tsuji E, Tsuji K, Suzuki S. 1975. Effect of polysaccharides on cholestrol metabolism (part 6) effect of various polysaccharides on serum and liver cholesterol levels in cholesterol-fet rats. Eiyogaku zashi 33: 273-281 https://doi.org/10.5264/eiyogakuzashi.33.273
  26. Kimura T, Tsuji K. 1993. Effects of the primary structure of alginate on fecal excretion of sodium in rats. Nippon Nogeikagaku Kaishi 67: 1177-1183 https://doi.org/10.1271/nogeikagaku1924.67.1177
  27. Tsai AC, Elias J, Kelley J, Lin RC, Robson JRK. 1976. Influence of certain dietary fibers on serum and tissue cholesterol levels in rats. J Nutr 106: 118-123 https://doi.org/10.1093/jn/106.1.118
  28. Cho EJ. 1999. Standardization and cancer chemopreventive activities of Chinese cabbage kimchi. PhD Dissertation. Pusan National University
  29. AOAC. 1990. Official Methods of Analysis. 15th ed. Association of Official Analytical Chemists, Washington, DC. p 60
  30. James GC, Sherman N. 1987. Microbiology: A laboratory manual. 2nd ed. The Benjamin/Cummings Pub., New-York. p 76
  31. Reeves PG, Nielsen FH, Fahey GC. 1993. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 123: 1939-1951 https://doi.org/10.1093/jn/123.11.1939
  32. Bucolo G, David H. 1973. Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem 19: 476-482
  33. Yao T, Sato M, Kobayashi Y, Wasa T. 1985. Amperometric assays of total and free cholesterol in serum by the combined use of immobilized cholesterol esterases and cholesterol oxidant reactors and peroxidase electrode in a flow injection system. Anal Biochem 149: 387-389 https://doi.org/10.1016/0003-2697(85)90587-1
  34. Kuk JL, Katzmarzyk PT, Nichaman MZ, Church TS, Blair SN, Ross R. 2006. Visceral fat is an independent predictor of all-cause mortality in men. Obesity 14: 336-341 https://doi.org/10.1038/oby.2006.43
  35. Considine RV, Sinha MK, Heiman MI, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CC, Mckee LJ, Bauer TL, Caro JF. 1996. Serum immunoreactive leptin concentrations in normal weight and obese humans. New Eng J Med 334: 292-295 https://doi.org/10.1056/NEJM199602013340503
  36. Huiqing Lu, Zhengbo D, Craig HKL, Catherine J, Anne B, Joseph CD. 1998. Obesity due to high fat diet decreases the sympathetic nervous and cardiovascular responses to intracerebroventricular leptin in rats. Brain Res 47: 331-335 https://doi.org/10.1016/S0361-9230(98)00086-0
  37. Hong KH, Kang SA, Kim SH, Choue RW. 2001. Effects of high fat diet on serum leptin and insulin level and brown adipose tissue UCP 1 expression in rats. Korean J Nutr 34: 865-871
  38. Choi SM. 2001. Antiobesity and anticancer effects of red pepper powder and kimchi. PhD Dissertation. Pusan National University
  39. Seal CJ, Mathers JC. 2001. Comparative gastrointestinal and plasma cholesterol responses of rats fed on cholesterol-free diets supplemented with guar gum and sodium alginate. British J Nutr 85: 317-324 https://doi.org/10.1079/BJN2000250
  40. Nyman M, Schweizer TF, Tyren S, Reimann S, Asp NG. 1990. Fermentation of vegetable fiber in the intestinal tract of rats and effects on fecal bulking and bile acid excretion. J Nutr 120: 459-466 https://doi.org/10.1093/jn/120.5.459
  41. Kishimoto Y, Wakabayashi S, Takeda H. 1995. Hypocholesterolemic effect of dietary fiber: relation to intestinal fermentation and bile excretion. J Nutr Sci Vitaminol (Tokyo) 41: 151-161 https://doi.org/10.3177/jnsv.41.151

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