The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)
- Volume 20 Issue 1 Serial No. 32
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- Pages.154-168
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- 2007
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
Effects of Agrimoniae Herba Ledebour on steptozotocin-induced Diabetic Mellitus in Rats.
선학차(仙鶴草) 추출물의 투여(投與)가 Streptozotocin으로 유발된 당뇨쥐에 미치는 영향
- Published : 2007.04.25
Abstract
Objective : The present study was carried out to investigate the preventive effect of Agrimonia pilosa Ledebour on Streptozotocin(STZ)-induced Diabetes mellitus. Method : Agrimonia pilosa Ledebour was given to rats with oral administration. The experimental animals were divided into 3groups : normal group of rats, control group of STZ-induced diabetic rats, sample group with Agrimonia pilosa Ledebour. The effect of Agrimonia pilosa Ledebour on STZ-induced diabetes was observed by measuring the survival rate of rats, weight of rats, FER, blood glucose, each organ weight of rat, total cholesterol, HDL, GOT, GPT & creatinine. Result : STZ caused hyperglycemia and hypoinsulinemia by a selectively destroying pancreatic