The Preparation of Polyacrylonitrile Diagnostic Membranes for Blood Glucose Measurements (2) : Effects of Blood Constituents on the Measurements of Glucose Concentration

혈당측정을 위한 폴리아크릴로니트릴 진단막의 제조(2) : 혈액속의 성분들이 글루코우즈의 농도 측정에 미치는 영향

  • Kwon, Suk-Ky (Department of Chemical System Engineering, Hongik University) ;
  • Choi, Mi-Ok (Department of Chemical System Engineering, Hongik University)
  • 권석기 (홍익대학교 과학기술대학 화학시스템공학과) ;
  • 최미옥 (홍익대학교 과학기술대학 화학시스템공학과)
  • Published : 2008.12.30

Abstract

Diagnostics membranes which were made of polyacrylonitrile were prepared for the measurements of blood glucose concentration. Final absorbances at 680nm through polyacrylonitrile diagnostic membranes were measured at various concentration of glucose in blood. It was found that the end-point results of varing absorbance values as time (K/S) had a linear relationship toward the blood glucose concentration. The effects of possible constituents in human blood on the glucose concentration measurements were examined. As a result, most of the chemicals did not affect seriously on the blood glucose measurements.

혈액 속에 있는 글루코우즈의 농도를 측정하기 위해 폴리아크릴로니트릴로 만들어진 진단막을 제조하였다. 혈액속의 글루코우즈의 농도를 변화시켜 가며 폴리아크릴로니트릴 진단막을 가지고 680nm에서의 최종흡광도를 측정하였다. 시간에 따른 흡광도 변화량(K/S)의 최종결과치가 글루코우즈의 농도가 증가함에 따라 직선적으로 증가함을 알 수 있었다. 혈액 속에 존재할 가능성이 있는 화합물들이 글루코우즈의 농도측정에 미치는 영향을 조사하였다. 그 결과 대부분의 화합물들이 글루코우즈의 농도측정에 큰 영향을 미치지 않는 것을 알 수 있었다.

Keywords

References

  1. T. Asano and T. Norioka, "Diabetes", Nihon Bungeisha, Tokyo (2000)
  2. K. Huh, "Diabetic Health", D&C, Seoul (2006)
  3. T. Asano, "Diabetic Food and Life style", Shufu-To-Seikatsusha Co., Tokyo (2005)
  4. S. Kwon, I. Park, and D. Yoon, "The Preparation of Polyacrylonitrile Diagonostic Membranes for Blood Glucose Measurements (1) : Effects of Temperature and Humidity on the Measurements of Glucose Concentration", Membrane Journal, 17, 4 (2007)
  5. J. Kim, "Diabetes : Diagnostics and Control", Ohsung, Seoul (1997)
  6. S. Kim, "Life Guide for Diabetes Control", Hyoseong, Seoul (1993)
  7. K. Lee, "Modern Disease Digest", Kuckminilbosa, Seoul (1992)
  8. Home Health Management Research Institute, "Diabetes", Kumyoung, Seoul (1992)
  9. S. Kwon, "Studies on the preparation of Diagnostic Membranes for Blood Glucose Measurements (3): Effects of Hematocrit on the Measurements of Glucose Concentration", Hongik Industrial Technology, 14 (2004)
  10. S. Kwon, "Studies on the Polyurethane Diagnostic Membrane for Diabetes (2): Effects of Additives in Membrane Formulations for the Measurement of Urine Glucose", Polymer (Korea), 18, 6 (1994)
  11. S. Kwon, "Studies on the Preparation of Diagnostic Membranes for Blood Glucose Measurements (2): Effects of Temperature on the Measurements of Glucose Concentration", Hongik Industrial Technology, 13 (2003)
  12. S. Kwon, "Studies on the preparation of Diagnostic Membranes fir Blood Glucose Measurements (1) : Model Experiments by using Microporous Polyurethane Membrane", Hongik Insustrial Technology, 12 (2002)
  13. S. Kwon, "Basic Studies on the Preparation of Diagnostic Membranes by Using Mult-i-Layered Gelatin Films to Measure Blood Glucose Level of Diabetcs", Membrane Journal, 8, 1 (1998)
  14. R. E. Kesting, "Synthetic Polymeric Membranes", Wiley. Interscience, New York (1985)
  15. S. Kwon, "Studies on the Muti-Layered Gelatin Diagnostic Membranes for Diabetes (2): Effects of Interferents in Blood on the Diffusion-Controlled Rates of Glucose", Membrane Journal, 9, 4 (1999)
  16. S. Kwon and B. Lee, "Studies on the Multi - Layered Gelatin Diagnostic Membranes for Diabetes (1): Effects of Temperature and Humidity on the Diffusion-Constrolled Rates of Glucose", Membrane Journal, 9, 2 (1992)
  17. S. Kwon, "A Study on the Preparation of Polyurethane Diagnostic Membrane for Urine Glucose Test", J. Kor. Ind. & Eng. Chem., 5, 6 (1994)
  18. S. Kwon, "A Study on the Preparation of Polyurethane Diagnostic Membrane for Urine Glucose Test", J. Kor. Ind. & Eng. Chem., 5, 6 (1994)
  19. S. Kwon, I. Park, and D. Yoon, "Studies on the preparation of polyurethane Diagnostic Membranes for Blood Glucose Measurements (5): Effects of Temperature and Humidity on the Measurements of Glucose Concentration", Membrane Journal, 17, 1 (2007)
  20. S. Kwon, "Studies on the Preparation of Diagnostic Membranes for Blood Glucose Measurements (4): Effects of Additives in Blood on the Measurements of Glucose Concentration", Hongik Industrial Technology, 15 (2005)
  21. S. Kwon, "Studies on the Muti-Layered Gelatin Diagnostic Membranes for Diabetes (2): Effects of Interferents in Blood on the Diffusion-Controlled Rates of Glucose", Membrane Journal, 9, 4 (1999)