Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

Study on anti-allergic effects of Arctii Fructus herbal acupuncture

우방자약침(牛蒡子藥鍼)의 항(抗)알러지 효과(效果)에 대한 연구(硏究)

  • Jang, Seok-Chang (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dong-Eui University) ;
  • Song, Choon-Ho (Dept. of Meridian & Acupoint, College of Oriental Medicine, Dong-Eui University)
  • 장석창 (동의대학교 한의과대학 경혈학교실) ;
  • 송춘호 (동의대학교 한의과대학 경혈학교실)
  • Published : 2008.03.27
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Abstract

Objectives : We studied on anti-allergic effects of Arctii Fructus Herbal Acupuncture(AFHA) and Arctii Fructus Herbal Acupuncture Solution(AF). Methods : In vivo, Animals were herbal-acupunctured AFHA at both ST36 three times for 5 days. Then, we investigated compound 48/80-induced active systemic anaphylaxis(ASA) using ICR mice and anti-DNP IgE-induced passive cutaneous anaphylaxis(PCA) using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase, IL-4 and TNF-a release from RBL-2H3 cells after treatment of AF of various concentrations. Results : In vivo, AFHA pretreatments at both ST36 inhibited compound 48/80-induced ASA. PCA was inhibited by AFHA pretreatments at both ST36. In vitro, AF treatments were not affect on cell viability and inhibited b-hexosaminidase, IL-4 and TNF-a release. Conclusions : These results suggest that AFHA and AF may be beneficial in the inhibition of allergic inflammatory response.

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