Spontaneously Occurring Chemodectoma in a Yorkshire Terrier Dog

  • Park, Chul (Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California) ;
  • Yoo, Jong-Hyun (BK21 Program of Integrative Network Systems for Veterinarians in Basic Science, Industrial Animals and Preventive Medicines, Konkuk University) ;
  • Kim, Dae-Young (Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri-Columbia) ;
  • Park, Hee-Myung (Department of Veterinary Internal Medicine, College of Veterinary Medicine Konkuk University)
  • Published : 2008.06.30

Abstract

A 7-year-old, intact female Yorkshire terrier dog was presented for coughing, anorexia, chest pain and dyspnea. Right lateral thoracic radiograph demonstrated a large mass shape on the heart base with decreased cardiac silhouette and severe right deviation of the trachea with the heart shifted to the left thoracic wall was observed on the ventrodorsal thoracic projection. Echocardiographic examination revealed a large rounded mass compressing left atrium around the heart base without signs of pericardial effusion. On computed tomographic (CT) findings, sagittal CT images depicted the possibility of cranial vena caval invasion and heart base involvement of the mass associated with biatrial compression. Dorsal CT image revealed the right deviation of trachea due to the heart base mass and markedly shrunk lung space was detected on the transverse CT image. Because the dog suddenly had died during the recovery from anesthesia after finishing CT scan, necropsy was performed. On gross findings, a large and lobulated mass was located at the base of the heart. A poorly-demarcated, infiltrative, multilobulated tumor composed of polyhedral cells in solid cellular sheets was confirmed based on histopathologic examination. This dog was diagnosed as a chemodectoma. This case report describes the clinical findings, diagnostic consistency of thoracic radiography, echocardiography and CT, and histopathologic confirmation in a spontaneously occurring chemodectoma with a Yorkshire terrier dog.

Keywords

References

  1. Atkins CE, Badertscher RR, Greelee P, Nash P. Diagnosis of an intracardiac fibrosarcoma using two-dimentional echocardiography. J Am Anim Hosp Assoc 1984; 20: 130-137
  2. Balaquer L, Romano J, Nieto JM, Vidal S, Alvarez C. Incidental finding of a chemodectoma in a dog: differential diagnosis. J Vet Diagn Invest 1990; 2: 339-341 https://doi.org/10.1177/104063879000200417
  3. Berg RJ, Wingfield W. Pericardial effusion in the dog: a review of 42 cases. J Am Anim Hosp Assoc 1984; 20: 721-730
  4. Blackmore J, Gorman NT, Kagan K, Hines S, Spencer C. Neurologic complications of a chemodectoma in a dog. J Am Vet Med Assoc 1984; 184: 475-478
  5. Cobb MA, Brownlie SE. Intrapericardial neoplasia in 14 dogs. J Small Anim Pract 1992; 33: 309-316 https://doi.org/10.1111/j.1748-5827.1992.tb01153.x
  6. Dean MJ, Strafuss AC. Carotid body tumors in the dog: a review and report of four cases. J Am Vet Med Assoc 1975; 166: 1003-1006
  7. Girard C, Helie P, Odin M. Intrapericardial neoplasia in dogs. J Vet Diagn Invest 1999; 11: 73-78 https://doi.org/10.1177/104063879901100112
  8. Hayes HM Jr. A hypothesis for the aetiology of canine chemoreceptor neoplasms, based upon an epidemiological study of 73 cases among hospital patients. J Small Anim Pract 1975; 16: 337-343 https://doi.org/10.1111/j.1748-5827.1975.tb05751.x
  9. Kamiyoshihara M, Kawashima O, Ishikawa S, Morishita Y. Mediastinal lymph node evaluation by computed tomographic scan in lung cancer. J Cardiovasc Surg (Torino) 2001; 42: 119-124
  10. Kaplan DK. Mediastinal lymph node metastases in lung cancer. Thorax 1992; 47: 332-333 https://doi.org/10.1136/thx.47.5.332
  11. Ko JP, Drucker EA, Shepard JA, Mountain CF, Dresler C, Sabloff B, McLoud TC. CT depiction of regional nodal stations for lung cancer staging. AJR Am J Roentgenol 2000; 174: 775-783 https://doi.org/10.2214/ajr.174.3.1740775
  12. Owen TJ, Bruyette DS, Layton CE. Chemodectoma in dogs. Compend Contin Educ Pract Vet 1996; 18: 253-265
  13. Oyama MA, Sisson DD. Cardiac troponin I concentration in dogs with cardiac disease. J Vet Intern Med 2004; 18: 831-839 https://doi.org/10.1111/j.1939-1676.2004.tb02629.x
  14. Park IC. Ultrasonographic diagnosis of metastatic intracavitary cardiac aortic tumor in a dog. J Vet Clin 2000; 17: 173-177
  15. Patnaik AK, Liu SK, Hurvitz AI, McClelland AJ. Canine chemodectoma (extra-adrenal paragangliomas): a comparative study. J Small Anim Pract 1975; 16: 785-801 https://doi.org/10.1111/j.1748-5827.1975.tb05813.x
  16. Swartout MS, Ware WA, Bonagura JD. Intracardiac tumors in two dogs. J Am Anim Hosp Assoc 1987; 23: 533-538
  17. Thomas WP, Sisson D, Bauer TG, Reed JR. Detection of cardiac masses in dogs by two-dimensional echocardiography. Vet Radiol 1984; 25: 65-72 https://doi.org/10.1111/j.1740-8261.1984.tb01911.x
  18. Walter JH, Rudolph R. Systemic, metastatic, eu- and heterotope tumors of the heart in necropsied dogs. Zentralbl Veterinarmed An 1996; 43: 31-45 https://doi.org/10.1111/j.1439-0442.1996.tb00426.x
  19. Ware WA, Hopper DL. Cardiac tumors in dogs: 1982-1995. J Vet Intern Med 1999; 13: 95-103
  20. Ware WA, Merkley DF, Riedesel DH. Intracardial thyroid tumor in a dog: diagnosis and surgical removal. J Am Anim Hosp Assoc 1994; 30: 20-23
  21. Weisse C, Soares N, Beal MW, Steffey MA, Drobatz KJ, Henry CJ. Survival times in dogs with right atrial hemangiosarcoma treated by means of surgical resection with or without adjuvant chemotherapy: 23 cases (1986-2000). J Am Vet Med Assoc 2005; 226: 575-579 https://doi.org/10.2460/javma.2005.226.575
  22. Yates WDG, Lester SJ, Mills JHL. Chemoreceptor tumors diagnosed at the Western College of Veterinary Medicine (1967-1979). Can Vet J 1980; 21: 124-129
  23. Youn JH, Lee SK, Park NY. Aortic body tumor in a dog. Korean J Vet Res 1982; 22: 247-251