The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
권호 표지

The Effects of Ssanggang-tang($Shu\bar{a}ngji\grave{a}ng-t\bar{a}ng$) on Rat with Induced Hyperlipidemia

쌍강탕(雙降湯)이 고(高)cholesterol 식이(食餌)로 유발(誘發)된 고지혈증(高脂血症) 백서(白鼠)에 미치는 영향(影響)

  • Lee, Jae-Hwi (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Lim, Seung-Min (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • An, Joung-Jo (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Jo, Hyun-Kyung (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Yoon-Sik (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol, In-Chan (Department of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Yoo, Ho-Rhyong (Department of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 이재휘 (대전대학교부속한방병원 심계내과학교실) ;
  • 임승민 (대전대학교부속한방병원 심계내과학교실) ;
  • 안정조 (대전대학교부속한방병원 심계내과학교실) ;
  • 조현경 (대전대학교부속한방병원 심계내과학교실) ;
  • 김윤식 (대전대학교부속한방병원 심계내과학교실) ;
  • 설인찬 (대전대학교부속한방병원 심계내과학교실) ;
  • 유호룡 (대전대학교부속한방병원 심계내과학교실)
  • Published : 2008.06.30
Download PDF
⟨ Previous Next ⟩

Abstract

Objective : Ssanggang-tang(SGT) is noted as an effective method to treat hyperlipidemia in China. The main purpose of this study was analysis of the effects of Ssanggang-tang(SGT) on rats induced with caused hyperlipidemia. Methods : We observed 3 experimental groups: normal, control, and SGT. Rats were provided a normal diet in the normal group, and the other groups were provided a hyperlipidemic diet to induce hyperlipidemia. After 2 weeks, SGT was treated in the SGT group. For 6 weeks, values related to hyperlipidemia were observed in the 3 experimental groups. Results : SGT decreased some values related to hyperlipidemia like total cholesterol, low density lipoprotein cholesterol(LDL cholesterol), triglyceride, acetocoenzyme A acetyltransferase(ACAT), and 3-hydroxy-3-methylglutaryl coenzyme A reductase(HMG-CoA reductase). However, it showed no effect on weight change or high density lipoprotein cholesterol(HDL cholesterol). Conclusion : These results suggest that SGT might be effective in treatment and prevention of hyperlipidemia.

Keywords