Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Ecotoxicological Effects of $CeO_2$ Nanoparticles on Soil Nematode Caenorhabditis elegans

토양선충 Caenorhabditis elegans를 이용한 세리아($CeO_2$) 독성연구

  • Roh, Ji-Yeon (Faculty of Environmental Engineering, College of Urban Science, University of Seoul) ;
  • Park, Young-Kwon (Faculty of Environmental Engineering, College of Urban Science, University of Seoul) ;
  • Choi, Jin-Hee (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
  • 노지연 (서울시립대학교 환경공학부 독성학연구실) ;
  • 박영권 (서울시립대학교 환경공학부 독성학연구실) ;
  • 최진희 (서울시립대학교 환경공학부 독성학연구실)
  • Published : 2008.06.30
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Abstract

In this study, three different sizes of cerium oxide ($CeO_2$) nanoparticles were synthesized and exposed to Caenorhabditis elegans to investigate the potential harmful effect of $CeO_2$ nanoparticles on the environment. The effects of the $CeO_2$ nanoparticles on C. elegans were assessed at multiple levels, such as with respect to stress response gene expression, growth, reproduction and mortality. Moreover, to test the ecotoxicological relevance of $CeO_2$-induced gene expression. The overall results suggest that $CeO_2$ nanoparticles may provoke ecotoxicity in C. elegans especially with respect to gene expression, reproduction and survival, which can comprise an important contribution to knowledge on the ecotoxicity of $CeO_2$ nanoparticles, about which little data are available. This is particularly valuable in the biomarker research on ecotoxicology, as ecological relevance is a crucial criterion for the applicability of the biomarker in field biomonitoring and ecological risk assessment.

Keywords

References

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