Primary Acalvaria in a Chihuahua Dog

치와와견에서 발생한 원발성 Acalvaria 증례

  • Choi, Ho-Jung (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Lim, Soo-Ji (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • An, Ji-Young (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • O, I-Se (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Jung, Gi-Young (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Cho, Sung-Whan (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University) ;
  • Lee, Young-Won (College of Veterinary Medicine, Research Institute of Veterinary Medicine, Chungnam National University)
  • 최호정 (충남대학교 수의과대학, 동물의과학연구소) ;
  • 임수지 (충남대학교 수의과대학, 동물의과학연구소) ;
  • 안지영 (충남대학교 수의과대학, 동물의과학연구소) ;
  • 오이세 (충남대학교 수의과대학, 동물의과학연구소) ;
  • 정기영 (충남대학교 수의과대학, 동물의과학연구소) ;
  • 조성환 (충남대학교 수의과대학, 동물의과학연구소) ;
  • 이영원 (충남대학교 수의과대학, 동물의과학연구소)
  • Published : 2009.02.27

Abstract

A three-week old female Chihuahua dog weighing 80 g was presented with the absence of skull palpation, suckling disability, and growth retardation. Physical examination revealed asymmetry of the lips slanting to the left side when feeding milk. Also there were head tilt to the left side and corneal ulcer of the left eye. The absence of the frontal and parietal bones were shown on radiographs. Lateral ventricular enlargement was identified on the ultrasonographic examination. On computed tomographs, frontal and parietal bone defect, ventricle enlargement, and intracranial arachnoid cyst were observed. The dog was dead after 1 day of presentation. The dog was diagnosed as the primary acalvaria by necropsy.

약 3주령된 80 g의 암컷 치와와견이 두부 촉진 시 두개골이 확인되지 않으며, 어미젖을 먹을 시 이상을 보이고 성장 저하의 증상을 지닌 채 내원하였다. 신체 검사에서 입과 두부의 좌측 기울어짐과 좌측 안구 각막의 손상을 확인하였다. 방사선 검사에서 전두골과 두정골의 골음영이 관찰되지 않았으며, 초음파 검사에서 측뇌실의 확장을 관찰하였다. 컴퓨터단층촬영 검사를 통해 전두골과 두정골의 결손, 뇌실의 확장, 지주막 낭종을 확인하였다. 환자는 내원 익일에 폐사하였다. 부검에 의해 원발성 acalvaria로 확정 진단하였다.

Keywords

References

  1. Amy ST. Principles of computed tomography and magnetic resonance imaging. In: Donald ET. Textbook of Veterinary Diagnostic Radiology. $5^{th}$ ed. Saunders Elsevier. 2007; 50-77
  2. Bianca S, Ingegnosi C, et al. Prenatal and postnatal findings of acrania. Arch Gynecol Obstet 2005; 271: 256-58
  3. Cherie R. Primary Acalvaria. J Diag Med Sono 2006; 22: 407-10 https://doi.org/10.1177/8756479306295831
  4. Cheryl PH, Jeannette JT, John CC. Am J Med Genet 1993; 46: 694-99 https://doi.org/10.1002/ajmg.1320460620
  5. Howard EE. Prenatal development. In: Howard EE. Miller's Anatomy of the Dog. 3rd ed. W.B. Saunders. 1993; 32-97
  6. Howard EE. The skeleton. In: Howard EE. Miller's Anatomy of the Dog. $3^{rd}$ ed. W.B. Saunders. 1993; 122-218
  7. Kathleen M, Raj PK, et al. Acalvaria and hydrocephalus: A case report and discussion of the literature. J Ultrasound Med 1999; 18: 783-87
  8. Khadikar VV, Khadikar AV, Nimbaklar AA, Kinnare AS. Acalvaria. Indian Pediatr 2004; 41: 618-20
  9. Leboucq N, Martinez PM, et al. Aplasia cutis congenital of the scalp with large underlying skull defect: a case report. Neuroradiology 1994; 36: 480-2 https://doi.org/10.1007/BF00593689
  10. Lorenzo DB, Cynthia AM, et al. Neural-tube defects. N Engl J Med 1999; 341: 1509-19 https://doi.org/10.1056/NEJM199911113412006
  11. Mason B, Michael C. ACE inhibitor fetopathy and hypocalvaria: The kidney-skull connection. Teratology 1991; 44: 485-95 https://doi.org/10.1002/tera.1420440503
  12. Shushovan C, Shizuo O, et al. Congenital frontal bone defect with intact overlying scalp. Child's Nerv Syst 1993; 9: 485- 87 https://doi.org/10.1007/BF00393559
  13. Suresh C, Meng KL, Victor YY. Fetal acalvaria with amniotic band syndrome. Arch Dis Child Fetal Neonatal Ed https://doi.org/10.1136/fn.82.1.F11