Rhabdoid tumor in the gluteal region of a Shit-tzu dog

  • Accepted : 2009.12.01
  • Published : 2009.12.31

Abstract

Rhabdoid tumor is an aggressive neoplasm of animals and human. It is similar with rhabdomyosarcoma histopathologically. But cellular origin of this neoplasm showed no striated muscle origin by immunohistological and ultrastructural studies. Castrated male Shit-tzu dog, 6 years old, had a mass in the left gluteal region near to the tail. The mass was examined histopathologically and immunohistologically. Histopathologically, the tumor was consisted of large polygonal cell with abundant eosinophilic cytoplasm. The nuclei in some cells were marked eccentrically located. Immunohistochemically, many neoplastic cells were positive for vimentin. These findings were similar to histopathological and immunohistological features of human rhabdoid tumor and few rhabdoid tumors in animals.

Keywords

References

  1. Beckwith JB. Wilms' tumour and other renal tumors of childhood: a selective review from the National Wilms' Tumor Study Pathology Center. Hum Pathol 1983, 14, 481-492 https://doi.org/10.1016/S0046-8177(83)80003-3
  2. Beckwith JB, Palmer NF. Histopathology and prognosis of Wilms tumors: results from the first national Wilms' tumor study. Cancer 1978, 41, 1937-1948 https://doi.org/10.1002/1097-0142(197805)41:5<1937::AID-CNCR2820410538>3.0.CO;2-U
  3. Haas JE, Palmer NF, Weinberg AG, Beckwith JB. Ultrastructure of malignant rhabdoid tumor of the kidney. A distinctive renal tumor of children. Hum Pathol 1981, 12, 646-657 https://doi.org/10.1016/S0046-8177(81)80050-0
  4. Hong CB, Van Meter PW, Latimer CL. Malignant rhabdoid tumour in the orbit of a horse. J Comp Pathol 1999, 121, 197-201 https://doi.org/10.1053/jcpa.1999.0311
  5. Izawa T, Yamate J, Takeda S, Kumagai D, Kuwamura M. Cutaneous rhabdoid tumor in a cat. Vet Pathol 2008, 45, 897-900 https://doi.org/10.1354/vp.45-6-897
  6. Kodet R, Newton WA Jr, Sachs N, Hamoudi AB, Raney RB, Asmar L, Gehan EA. Rhabdoid tumors of soft tissues: a clinicopathologic study of 26 cases enrolled on the intergroup rhabdomyosarcoma study. Hum Pathol 1991, 22, 674-684 https://doi.org/10.1016/0046-8177(91)90289-2
  7. Parham DM, Weeks DA, Beckwith JB. The clinicopathologic spectrum of putative extrarenal rhabdoid tumors. An analysis of 42 cases studied with immunohistochemistry or electron microscopy. Am J Surg Pathol 1994, 18, 1010-1029 https://doi.org/10.1097/00000478-199410000-00005
  8. Schauer G, Moll R, Walter JH, Rumpelt HJ, Goltenboth R. Malignant rhabdoid tumor in the gastric wall of an aged orangutan (Pongo pygmaeus). Vet Pathol 1994, 31, 510-517 https://doi.org/10.1177/030098589403100502
  9. Steele KE, Schulman FY, Mena H, Strimple EO. Rhabdoid tumor in the brain of a dog. Vet Pathol 1997, 34, 359-363 https://doi.org/10.1177/030098589703400415
  10. Weeks DA, Malott RL, Zuppan CW, Liwnicz BH, Beckwith JB. Primitive cerebral tumor with rhabdoid features: a case of phenotypic rhabdoid tumor of the central nervous system. Ultrastruct Pathol 1994, 18, 23-28 https://doi.org/10.3109/01913129409016270