The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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The Relationship between Metabolic Syndrome and Erythrocyte Deformability in Small Vessel Disease Stroke Patients

중풍환자에서 대사증후군과 적혈구변형능의 관련성

  • Leem, Jung-Tae (Dept. of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Su-Jyung (Dept. of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung-Hee University) ;
  • Kim, Mi-Young (Dept. of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung-Hee University) ;
  • Choi, Won-Woo (Dept. of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung-Hee University) ;
  • Jung, Woo-Sang (Dept. of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung-Hee University) ;
  • Cho, Ki-Ho (Dept. of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung-Hee University) ;
  • Park, Sung-Wook (Stroke & Neurological disorders center, East-West Neo Medical Center, College of Oriental Medicine, Kyung-Hee University) ;
  • Ko, Chang-Nam (Stroke & Neurological disorders center, East-West Neo Medical Center, College of Oriental Medicine, Kyung-Hee University) ;
  • Lee, Jung-Sup (TKM Converging Research Division Brain Disease Research Center, Korea Institute of Oriental Medicine)
  • 임정태 (경희대학교 한의과대학 심계내과) ;
  • 박수경 (경희대학교 한의과대학 심계내과) ;
  • 김미영 (경희대학교 한의과대학 심계내과) ;
  • 최원우 (경희대학교 한의과대학 심계내과) ;
  • 정우상 (경희대학교 한의과대학 심계내과) ;
  • 조기호 (경희대학교 한의과대학 심계내과) ;
  • 박성욱 (경희대학교 동서신의학병원 중풍.뇌질환센터) ;
  • 고창남 (경희대학교 동서신의학병원 중풍.뇌질환센터) ;
  • 이정섭 (한국한의학연구원 한의융합연구본부 뇌질환연구센터)
  • Published : 2009.12.30
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Abstract

Objectives : The aim of this study was to assess the relationship between metabolic syndrome and erythrocyte deform ability in acute stroke patients. Methods : Among 88 of the recruited patients, 52 were diagnosed as metabolic syndrome. We assessed their general characteristics, risk factors. We compared the assessed variables between metabolic syndrome and control group. We analyzed the relationship between metabolic syndrome and erythrocyte deform ability. We analyzed relationship between cardiovascular risk factors and erythrocyte deformability. Results : The general characteristics waist and hip circumference, waist/hip ratio were higher in metabolic syndrome group. The metabolic syndrome group was also diagnosed with hypertension, DM, and hyperlipidemia more often than the control group. The blood test metabolic syndrome group showed higher triglycerides, total lipids, fasting blood sugar, and 2 hours postprandial plasma glucose level and lower HDL-cholesterol than the control group. There were more patients diagnosed with Dampness-Phlegm in the metabolic syndrome group. There were more patients showing lower erythrocyte deform ability in the metabolic syndrome group. The plasma homocysteine level was negatively correlated with erythrocyte deform ability. Conclusion : The results reconfirmed that the risk factors are more in metabolic syndrome group. The results indicated that metabolic syndrome lead to a lower erythrocyte deform ability in small vessel disease stroke patients. The Plasma homocysteine level was negatively correlated with erythrocyte deform ability.

Keywords

References

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