하거허 유침 및 고주파 전침이 흰쥐의 장운동에 미치는 영향

Effect of Acupuncture and High Frequency Electroacupuncture at $ST_{39}$ on Intestinal Motility in Rats

  • 이은경 (대전대학교 한의과대학 침구학교실) ;
  • 최은희 (대전대학교 한의과대학 침구학교실) ;
  • 전주현 (대전대학교 한의과대학 침구학교실) ;
  • 김영일 (대전대학교 한의과대학 침구학교실)
  • Lee, Eun-Kyoung (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Choi, Eun-Hee (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Jeon, Ju-Hyon (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University) ;
  • Kim, Young-Il (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Daejeon University)
  • 발행 : 2009.04.20

초록

Objectives : The aim of this study was to observe the effect of acupuncture and high frequency electroacupuncture at $ST_{39}$ on intestinal motility in rats. Methods: We made over-activated state of intestinal motility with carbachol and suppressed state of intestinal motility with loperamide in rat and carried out needle retention acupuncture and high frequency electroacupuncture at $ST_{39}$ or sham point in rat divided into pre-treatment group and post-treatment group. We fed charcoal to them after the treatment and measured the travel rate of charcoal in the gastrointestinal tract to observe intestinal motility. Results : Examining intestinal motility of normal rat treated with needle retention acupuncture at $ST_{39}$ significantly suppressed intestinal motility. Pre-treatment of needle retention acupuncture significantly suppressed intestinal motility in rat which over-activated with carbachol. Pre-treatment and post-treatment of high frequency electroacupuncture significantly suppressed intestinal motility in rat which over-activated with carbachol. All of the pre-treatment and post-treatment of needle retention acupuncture, high frequency electroacupuncture showed no significant effect than control group on intestinal motility of rat which was suppressed with loperamide. Conclusions : These results suggest that acupuncture and high frequency electroacupuncture at $ST_{39}$ have preventive and therapeutic effects on over-activated intestinal motility, and high frequency electroacupuncture is more effective.

키워드

참고문헌

  1. 추교영, 최명규, 최황, 이동수, 김진일, 김성수, 방춘상, 박수헌 등. 우리나라 농촌지역사회 주민의 위장관 증상 유병률. 대한소화관운동학회지. 2006 ; 6 : 31-43.
  2. de Wit MAS, Koopmans MPG, Kortbeek LM, Wannet WJB, Vinje J, van Leusden F, Bartelds AIM, van Duynhoven YTHP. Sensor, a population-based cohort study on gastroenteritis in the Netherlands, incidence and etiology. Am J Epidemiol, 2001 ; 154 : 666-74. https://doi.org/10.1093/aje/154.7.666
  3. Herikstad H, Yang S, Van Gilder TJ, Vugia D, Hadler J, Blake P, Deneen V, Shiferaw B, Angulo FJ, A population-based estimate of the burden of diarrhoeal illness in the United States : FoodNet, 1996-7. Epidemiol Infect. 2002 ; 129 : 9-17.
  4. Scallen E, Fitzgerald M, Collins C, Daly K, Devine M, Igoe D, Quigley T, Robinson T, Smyth B. Acute gastroenteritis in Northern Ireland and the Republic Ireland: a telephone survey. Commun Dis Public Health. 2004 ; 7 : 61-7.
  5. Talley NJ, Stanghellini V, Heading RC. Functional gastroduodenal disorders. Gut. 1999 ; 45(Suppl 2) : 37-42.
  6. 박주언, 유범희. 기능성 위장관 장애의 정신과적 치료. 대한소화관운동학회지. 2004 ; 10(1) : 1-14.
  7. Tillisch K. Complementary and alternative medicine for functional gastrointestinal disorders. Gut. 2000 ; 55 : 593-6.
  8. 대한침구학회 교재편찬위원회 편저. 침구학(하). 파주 : 집문당. 2008 ; 291-330.
  9. 박양춘, 조정효, 손창규, 홍권의, 정인철, 강위창, 최선미. 기능성 소화불량증에 대한 침치료의 효과 : 무작위배정 대조군연구. 대한침구학회지. 2007 ; 24(1) : 1-12.
  10. Lim B, Manheimer E, Lao L, Ziea E, Wisniewski J, Liu J, Berman B. Acupuncture for treatment of irritable bowel syndrome. Cochrane Database Rev. 2006 ; CD005111.
  11. 대한침구학회 교재편찬위원회 편저. 침구학(상) 파주 : 집문당. 2008 ; 66.
  12. 최은희, 이은경, 전주현, 양기영, 김영일, 이현. 삼음교 유침, 저주파 및 고주파 전침이 흰쥐의 항진 된 장운동에 미치는 영향. 대한침구학회지. 2008 ; 25(5) : 139-49.
  13. 이성환, 임윤경, 이현. 삼음교 유침, 저주파 및 고주파 전침의 전.후 처치가 실험적으로 억제된 흰쥐의 장운동에 미치는 영향. 대한침구학회지. 2008 ; 25(4) : 105-16.
  14. 남세현, 이현. 合谷에 대한 유침, 저주파 및 고주파 전침이 흰쥐의 장운동에 미치는 영향. 대한침구학회지. 2008 ; 25(4) : 11-29.
  15. 서용석, 홍권의. 曲池에 대한 유침 및 전침자극이 흰쥐의 장운동에 미치는 영향. 대한침구학회지. 2008 ; 25(4) : 59-69.
  16. 조은희, 박민철, 김대중, 이호섭, 조남근, 주영승, 육태한, 유윤조. 足三里, 上巨虛, 下巨虛의 配穴에 따른 電鍼의 실험적 연구. 대한침구학회지. 2006; 23(5) : 79-92.
  17. 윤정안, 유윤조, 조남근, 손인철, 이호섭, 이준무, 김경식. 鍼과 電鍼 자극시 白鼠의 性別과 週齡 및 經穴配合이 小陽 輸送能에 미치는 영향. 대한침구학회지. 2007 ; 24(1) : 179-93.
  18. Stephen M. Collins. Translating symptoms into mechanisms : functional GI disorders. Adv Physiol Educ. 2007 ; 31(4) : 329-31. https://doi.org/10.1152/advan.00058.2007
  19. 서울대학교 의과대학. 소화기학. 서울 . 서울대학교출판사. 1993 : 183-96.
  20. Wilhelmsen I. Somatization, sensitization, and functional dyspepsia. Scand J Psychol. 2002 ; 43(2) : 177-80. https://doi.org/10.1111/1467-9450.00284
  21. Schwetz IF, Bradesi S, Mayer, Mayer EA. The pathophysiology of irritable bowel syndrome. Minerva Med. 2004 ; 95 : 419-26.
  22. Collins SM. Translating symptoms into mechanisms: functional GI disorders. Adv Physiol Educ. 2007 ; 31(4) : 329-31. https://doi.org/10.1152/advan.00058.2007
  23. Sodipo JO, Falaiye JM. Acupuncture gastric acid studies. Am J Chin Med. 1979 ; 7(4) : 356-61. https://doi.org/10.1142/S0192415X79000337
  24. Salvi E, Posotilli A, Romiti P, Bedogni G, Pedrazzoli C. Gastroscopic aspects of Duodenal ulcer before and after acupuncture treatment. Minerva Med. 1983 ; 74(42) : 2541-6.
  25. Shen D, Wei D, Liu B, Zhang F. Effect of electroacupuncture on gastin, mast cell and gastric mucosal barrier in the course of protecting rat stress peptic ulcer. Ahen Ci Yan Jiu. 1995 ; 20(3) : 46-9.
  26. Shen D, Liu B, Wi D, Zhang F, Chen Y. Effects of electroacupuncture on central and peripheral monoamine neurotransmitter in the course of protecting rat stress peptic ulcer. Zhen Ci Yan Jiu 1994 ; 19(1) : 51-4.
  27. Jin HO, Shou L, Lee KY, Chang M, Chey WY. Inhibition of acid secretion by electrical acupuncture is mediated via beta-endorphin and somatostatin. Am J Physiol. 1996 ; 271(3 Pt 1) : G524-30.
  28. Qian L, Peters LJ, Dhen JD. Effects of electroacupunctureon gastric migrating myoelectrical complex in dogs. Dig Dis Sci. 1999 ; 44(1) : 56-62. https://doi.org/10.1023/A:1026645931867
  29. Cheng X, Yang JB. Effects of chronoacupuncture na ja fa on gastric acid secretion, plasma gastrin and prostaglandin E1 in patients with peptic ulcer. Zhong Xi Yi Jie He Za Zhi. 1991 ; 11 (2) : 91-3, 68-9.
  30. 김정제. 最新鍼灸學. 서울 : 成輔社. 1995 : 211-3.
  31. 윤정안, 유윤조, 김강산, 김경식, 김홍훈, 김대중, 조남근. 전침의 parameters에 대한 실험적 연구. 대한침구학회지 2005 ; 22(1) : 145-53.