Mycobiology

The Korean Society of Mycology (한국균학회)
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In Vitro Antifungal Activity of Equol against Candida albicans

  • Lee, Jeong-Ah (Department of Cell Biology, College of Medicine, Konyang University) ;
  • Che, Hee-Youn (Department of Cell Biology, College of Medicine, Konyang University)
  • Received : 2010.06.01
  • Accepted : 2010.08.17
  • Published : 2010.12.31
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Abstract

In this study, we demonstrate that equol has fungicidal activities against Candida albicans. The minimum inhibitory and minimum fungicidal concentrations of equol against C. albicans were 516 and $1,032{\mu}M$, respectively. Two separate viability assays found that equol changed the integrity of the C. albicans cell membrane, possibly by formation of membrane lesions. Scanning electron microscopy demonstrated ultrastructural changes.

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References

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