Environmental Analysis Health and Toxicology

The Korean Society of Environmental Health and Toxicology (환경독성보건학회)
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Effectiveness of Scirpi rhizoma Ethanol Extract on Skin Whitening Using in vitro Test

삼릉 에탄올추출물의 in vitro 피부 미백 유효성

  • Ko, Ju-Young (Department of Public Health, Graduate School, Keimyung University) ;
  • Kim, Young-Chul (Department of Public Health, Graduate School, Keimyung University)
  • 고주영 (계명대학교 대학원 공중보건학과) ;
  • 김영철 (계명대학교 대학원 공중보건학과)
  • Published : 2010.03.31
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Abstract

The purpose of this study is to evaluate the effectiveness of Scirpi rhizoma ethanol extract (SREE) on skin whitening using in vitro test. In the antioxidative activities, it was found that SREE contains 38.9 mg/g of polyphenol and 74.5 mg/g of flavonoid in total. In the electron donating ability, SREE showed a dose-dependent response, showing a high antioxidative capacity of 86.1% at 1000 ppm. It was found that the maximum permissible level of SREE to Melan-a cells was over 200 ppm, showing a quite low toxicity of SREE against Melan-a cells. Both in the inhibitory measurement for tyrosinase activity and melanogenesis using Melan-a cells, SREE presented a dose-dependent response with excellent efficacy.

Keywords

References

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